Tuesday 5 November
6 November
Presentation Keynote Chair Plenary Keynote Forum /
Workshop
Exhibitor
[Schedule with Sessions only]
DAY 1ROOM 3AROOM 3BHALL 1BHALL 1C11a11b11cInnovation & Career ZoneTraining Zone
DAY 2
DAY 1ROOM 3AROOM 3BHALL 1BHALL 1C11a11b11cInnovation & Career ZoneTraining Zone
DAY 2
08:00 Arrival, registration & welcome coffee 08:00
08:05 08:05
08:10 08:10
08:15 08:15
08:20 08:20
08:25 08:25
08:30 08:30
08:35 08:35
08:40 08:40
08:45 ELRIG Annual Review
Chairs: Steve Rees, AstraZeneca 
08:45
08:50 08:50
08:55 Early Career Professionals Overview - Del Trezise (ELRIG ECP Workgroup Leader)
08:55 (10 mins)
08:55
09:00 09:00
09:05 Conference & Plenary Keynote Introduction
Chairs: Catherine Kettleborough, LifeArc 
09:05
09:10 09:10
09:15 Plenary Keynote - Day 1
Turning science into medicine: Hot trends and the business landscape
09:15 (50 mins)
Mene Pangalos, AstraZeneca 
09:15
09:20 09:20
09:25 09:25
09:30 09:30
09:35 09:35
09:40 09:40
09:45 09:45
09:50 09:50
09:55 09:55
10:00 CamBioScience Training Zone
10:00 (5 mins)
We will run our VR experience with CRISPR and ORGANOID practicals throughout the day, feel free to visit the training area anytime! There will be a fun quiz game using our OBRIZUM platform throughout ...[More]
10:00
10:05 Coffee CamBioScience Training Zone Cerebral Organoids by Dr Madeline Lancaster (University of Cambridge)
10:05 (45 mins)
10:05
10:10 10:10
10:15 10:15
10:20 10:20
10:25 10:25
10:30 10:30
10:35 10:35
10:40 10:40
10:45 10:45
10:50 Cellular Models of Disease
Session Introduction
10:50 (10 mins)
Paul Andrews, National Phenotypic Screening Centre Dr Robert Vries, Hubrecht Organoid Technology 
Chemical biology - re-defining target tractability and therapeutic class - Track sponsored by Charles River Laboratories
Session Introduction
10:50 (10 mins)
Marcus Bantscheff, Cellzome A GSK company  Satpal Virdee, University of Dundee 
Big Data & Artificial Intelligence
Session Introduction
10:50 (10 mins)
Ola Engkvist, AstraZeneca  Hugo Ceulemans , Janssen Pharmaceutica  
BPS - Targeting ion channels for drug discovery - Track sponsored by Charles River Laboratories
Session Introduction
10:50 (10 mins)
Sarah Nickolls, GlaxoSmithKline  David Kendall, Pharmnovo 
10:50
10:55 10:55
11:00 Cellular Models of Disease
What goes around comes around in drug discovery: from organs to targets and back again
11:00 (30 mins)
Paul Andrews, National Phenotypic Screening Centre 

Accelerating drug discovery for glioblastoma: the convergence of patient derived models, CRISPR engineering and phenotypic screening
11:30 (30 mins)
Prof Steven Pollard, University of Edinburgh 
Chemical biology - re-defining target tractability and therapeutic class - Track sponsored by Charles River Laboratories
Structure-based PROTAC design for drugging undruggable cancer targets
11:00 (30 mins)
Prof Alessio Ciulli, University of Dundee 

Diverse binding modes for a single interface: a case study in de novo cyclic peptide binding to the BET bromodomains
11:30 (30 mins)
Louise Walport, The Francis Crick Institute/Imperial College London 
Big Data & Artificial Intelligence
Artificial Intelligence: the story so far and the next chapter for drug discovery
11:00 (30 mins)
Sam Genway, Tessella 

Development of FAIR data methods in Life Science and Drug Discovery research
11:30 (30 mins)
Philip Gribbon, Fraunhofer IME ScreeningPort 
BPS - Targeting ion channels for drug discovery - Track sponsored by Charles River Laboratories
Activation of mechanosensitive TREK potassium channels – a therapeutic strategy for the treatment of pain
11:00 (30 mins)
Prof Alistair Mathie, University of Kent 

Screening for activators of K2P channels - A target class approach to identify novel analgesics
11:30 (30 mins)
Paul Wright, LifeArc 
Brooks Life Sciences and Titian Software Workshop
11:00 (60 mins)
Increase sample processing efficiency and protect sample integrity with full data visibility and inventory management Modern day drug discovery and biobanking applications involving both biological...[More]
Sartorius Workshop - Live-cell analysis in combination with advanced flow cytometry: Enhancing biological insight
11:00 (80 mins)
To enable a greater understanding of disease and potential therapy, researchers are seeking more translational assays to better describe the clinical situation. To meet these requirements has resulte...[More]
British Society of Nanomedicine Workshop
11:00 (90 mins)
Enhancing Therapeutics - A Nano Approach
11:00
11:05 11:05
11:10 11:10
11:15 11:15
11:20 11:20
11:25 11:25
11:30 11:30
11:35 11:35
11:40 11:40
11:45 11:45
11:50 11:50
11:55 11:55
12:00 Miltenyi Biotec Ltd
PLATINUM SPONSOR PRESENTATION - Automation meets cell separation: primary cells for drug discovery assays PRESENTER - Lotta Räty ABSTRACT - Whether you are performing killing assays, immunophenotyping...[More]
Poster Spotlight Presentations - Chemical biology
LifeArc Index Set: Utility for assessing target tractability and performance in a phenotypic screen.
12:00 (15 mins)
Miss Afrah Sattikar, LifeArc 
Poster Spotlight Presentations - Big Data & AI
Discovering Novel Therapeutic Targets Using Large Biomedical Knowledge Graphs
12:00 (15 mins)
Dr Arwa Raies, European Bioinformatics Institute (EMBL-EBI) 
Poster Spotlight Presentations - BPS
A Higher-Throughput Approach to Investigate Cardiac Contractility In Vitro Under Physiological Mechanical Conditionsct
12:00 (10 mins)
Dr Matthias Gossmann, innoVitro GmbH 
CamBioScience Training Zone CRISPR virtual lecture by Dr Oliver Baker (King's College London)
12:00 (30 mins)
12:00
12:05 12:05
12:10 Metrion Biosciences Limited
INDUSTRY INSIDER TALK. PRESENTER - Dr Marc Rogers TITLE - Potent and selective state-dependent Cav2.2 calcium channel modulators with efficacy in preclinical pain models and human tissue ABSTRACT - T...[More]
12:10
12:15 Charles River
TITLE - Discovery of New Therapeutics through the fusion of small and large molecules PRESENTER - Diarmuid Kenny ABSTRACT - The fusing of small and large molecule drugs via novel chemical linkers is...[More]
Thermo Fisher Scientific
TITLE - On the way to Artificial Intelligence: Feeding data hungry Machine Learning Algorithms using Thermo Scientific Momentum Lab Automation Systems PRESENTER - Evelyne Ploquin - Program Manager, St...[More]
12:15
12:20 Promega UK Ltd
TITLE - Measurement of kinase inhibitor target engagement in live-cells & mechanistic analysis of PROTAC-mediated targeted degradation of kinase targets PRESENTER - Craig Malcolm ABSTRACT - Promega...[More]
Genedata AG
TITLE - Genedata Imagence® - Deep Learning Automates the Analysis of Cell Painting Assays PRESENTER - Cameron Scott - ABSTRACT - Here we show how the new software solution Genedata Imagence enabled th...[More]
12:20
12:25 Eurofins Discovery
TITLE - Evolution of Contract Research Organizations to Contract Innovation Organizations? PRESENTER - : Carol Austin, PhD, Director of Biology, Integrated Drug Discovery, Eurofins Discovery (formerly...[More]
CAS
TITLE - Conquer the Chaos PRESENTER - Dr Jonathan Agbenyega ABSTRACT - Everyone is investing in AI, big data, and the digitalization of workflows to unlock R&D productivity. Unfortunately, technology ...[More]
12:25
12:30 Lunch & Posters CamBioScience Training Zone Cerebral Organoids by Dr Madeline Lancaster (University of Cambridge)
12:30 (90 mins)
12:30
12:35 12:35
12:40 12:40
12:45 12:45
12:50 12:50
12:55 12:55
13:00 13:00
13:05 13:05
13:10 13:10
13:15 13:15
13:20 13:20
13:25 13:25
13:30 13:30
13:35 13:35
13:40 13:40
13:45 13:45
13:50 13:50
13:55 13:55
14:00 Cellular Models of Disease
Organoids: A Patient in the lab
14:00 (30 mins)
Dr Robert Vries, Hubrecht Organoid Technology 
Chemical biology - re-defining target tractability and therapeutic class - Track sponsored by Charles River Laboratories
Chemical targeting of deubiquitinating enzymes for cancer therapy
14:00 (30 mins)
Sara Buhrlage , Dana-Farber Cancer Institute 
Big Data & Artificial Intelligence
Embedding Machine Learning into Medicinal Chemistry – Application of Neural Networks in Real Life Drug Discovery Projects
14:00 (30 mins)
Werngard Czechtizky , AstraZeneca 
BPS - Targeting ion channels for drug discovery - Track sponsored by Charles River Laboratories
GABAA Receptor Subtype Selective Compounds – Where Are We Now?
14:00 (30 mins)
Prof John Atack, Medicines Discovery Institute 
Beckman Coulter Life Sciences & Labcyte Inc Workshop
14:00 (60 mins)
How Echo Acoustic Liquid Handling Can Improve Your Drug Discovery Workflows Presented by John Lesnick - Applications Manager A greater emphasis on looking back will provide fruitful direction to...[More]
Early Career Professionals - Careers in Drug Discovery: Where to next?
14:00 (60 mins)
Are you a post-doc, postgraduate, early career researcher/ professional (ECP) scientist looking to start or build your career in drug discovery? If so, understanding the wide array of opportunities an...[More]
14:00
14:05 14:05
14:10 14:10
14:15 14:15
14:20 14:20
14:25 14:25
14:30 Poster Spotlight Presentations - Cellular Models of Disease
Identification of novel drug targets for Parkinson’s disease using an iPSC-derived neuronal phenotypic screening platform
14:30 (15 mins)
Dr Brent Ryan, University of Oxford 
Poster Spotlight Presentations - Chemical biology
Development of affinity and fluorescent probes to elucidate the mechanism of small molecule modulators of neurogenesis
14:30 (15 mins)
Miss Rachel Sim, University of Oxford 
Poster Spotlight Presentations - Big Data & AI
Expression Data Integration: Advancing Immuno-Oncology Target Discovery
14:30 (15 mins)
Dr Frank Staubli, Nebion AG 
Poster Spotlight Presentations - BPS
Ligand-gated ion channels involved in pain pathways: An automated patch clamp study
14:30 (15 mins)
Dr Alison Obergrussberger, Nanion Technologies GmbH 
14:30
14:35 14:35
14:40 14:40
14:45 Cellular Models of Disease
3D imaging reveals effective killing of breast tumor organoids by engineered T cells at a single cell level
14:45 (30 mins)
Ms Florijn Dekkers, Princess Máxima Centre 
Chemical biology - re-defining target tractability and therapeutic class - Track sponsored by Charles River Laboratories
Towards Next Generation Chemical Probes
14:45 (30 mins)
Keriann Backus , UCLA 
Big Data & Artificial Intelligence
Data Science and AI approaches to Drug Target Validation and repurposing
14:45 (30 mins)
Prof Michael Barnes, Centre for Translational Bioinformatics, William Harvey Research Institute, Queen Mary University of 
BPS - Targeting ion channels for drug discovery - Track sponsored by Charles River Laboratories
Targeting voltage-gated calcium channels in disease
14:45 (30 mins)
Prof Gary Stephens, University of Reading 
CamBioScience Training Zone CRISPR virtual lecture by Dr Oliver Baker (King's College London) and Dr Ben Davies (University of Oxford)
14:45 (30 mins)
14:45
14:50 14:50
14:55 14:55
15:00 15:00
15:05 15:05
15:10 15:10
15:15 Poster Spotlight Presentations - Cellular Models of Disease
Morphometric imaging of organoids for toxicology and assessment of therapeutic efficacy.
15:15 (15 mins)
Dr James Noble, National Physical Laboratory 
Labcyte Inc.
TITLE - Beckman and Labcyte: Dawning of a new Liquid Handling Era PRESENTER - Devin Donnelly, European Sales Manager
Pelago Bioscience AB
TITLE - Navigate the proteome with CETSA® MS PRESENTER - Stina Lundgren ABSTRACT - CETSA MS is a proteome-wide measurement of cellular target engagement using mass spectrometry for generating thermal ...[More]
Charles River
TITLE - Realise the full potential of your ion channel targets with Charles River PRESENTER - Juha Kammonen ABSTRACT - Join us for a discussion on how the Charles River ion channel team and the tech...[More]
15:15
15:20 Merck
TITLE - Partial PROTACs for Targeted Protein Degradation PRESENTER - Hugo Viana ABSTRACT - An emerging strategy in drug discovery to access difficult-to-treat diseases is targeted protein degradation....[More]
SLAS - Society for Laboratory Automation and Screening
TITLE - SLAS’s Growing AIm in Artificial Intelligence and Big Data PRESENTER - Dr. Mark Wigglesworth, Director Hit Discovery, AstraZeneca Discovery Sciences ABSTRACT - Dr. Wigglesworth will discuss ...[More]
Formulatrix, Inc.
TITLE - Scaling Organoid Culture using MANTIS ® Liquid Handler: A Case Study with MIT PRESENTER - Dan Lord ABSTRACT - Organoids allow researchers to study tissue biology with remarkable fidelity, a ...[More]
15:20
15:25 Cisbio
TITLE - HTRF Assays for Target Biology identification and Validation in Drug Discovery PRESENTER - Louise Affleck PhD ABSTRACT - Cisbio has developed easy to use, robust + reliable HTRF assays for mos...[More]
GE Healthcare Life Sciences
TITLE - The Evolution of High Content Analysis PRESENTER - Mark J. Graham - High Content Analysis - Sales Specialist (IN Cell Analyzer, Phenoglyphs and Cell DIVE)
LGC - ATCC
TITLE - TRC: Introducing a comprehensive range of high quality research chemical’s and custom synthesis solutions PRESENTER - Joe Lackey PhD
15:25
15:30 Coffee CamBioScience Training Zone Cerebral Organoids by Dr Madeline Lancaster (University of Cambridge)
15:30 (30 mins)
15:30
15:35 15:35
15:40 15:40
15:45 15:45
15:50 15:50
15:55 15:55
16:00 Cellular Models of Disease
Reducing attrition in drug discovery through the use of human translational cellular models
16:00 (30 mins)
Wendy Rowan, GlaxoSmithKline 

CRISPR/Cas-assisted genetics in intestinal organoids
16:30 (30 mins)
Dr Bon-Kyoung Koo, IMBA - Institute of Molecular Biotechnology of Austrian Academy of Sciences 
Chemical biology - re-defining target tractability and therapeutic class - Track sponsored by Charles River Laboratories
Activity-Based Analyses of Ubiquitin E3 Ligases
16:00 (30 mins)
Satpal Virdee, University of Dundee 

Understanding and Manipulating Protein-Protein Interactions Using Chemical Biology Approaches
16:30 (30 mins)
Dr David Andrews, AstraZeneca 
Big Data & Artificial Intelligence
Deep Generative Models for 3D Compound Design
16:00 (30 mins)
Prof Charlotte Deane, Department of Statistics, University of Oxford 

AI(d) in navigating small molecule space
16:30 (30 mins)
Hugo Ceulemans , Janssen Pharmaceutica  
BPS - Targeting ion channels for drug discovery - Track sponsored by Charles River Laboratories
A story of collaboration: Ion Channels for Drug Discovery
16:00 (30 mins)
Dr Kelly Gatfield, GSK 

Translational Neuroscience for Ion Channels
16:30 (30 mins)
Dr John Hutchison , Autifony 
Charles River Laboratories Workshop - Navigating your journey from HTS to MOA
16:00 (60 mins)
“Navigating your journey from HTS to MOA” Learn how to achieve your goals using a collaborative process, innovative science and robust technologies Delivering HTS campaigns collaboratively 16:00 –...[More]
16:00
16:05 16:05
16:10 16:10
16:15 16:15
16:20 16:20
16:25 16:25
16:30 16:30
16:35 16:35
16:40 16:40
16:45 16:45
16:50 16:50
16:55 16:55
17:00 Drinks reception & posters 17:00
17:05 17:05
17:10 17:10
17:15 17:15
17:20 17:20
17:25 17:25
17:30 Early Career Professionals - Careers in Drug Discovery: Network like a Boss
17:30 (60 mins)
Are you a post-doc, postgraduate, early career researcher/professional (ECP) scientist looking to start or build your career in drug discovery? If so, building and managing your network of contacts is...[More]
17:30
17:35 17:35
17:40 17:40
17:45 17:45
17:50 17:50
17:55 17:55
18:00 18:00
18:05 18:05
18:10 18:10
18:15 18:15
18:20 18:20
18:25 18:25
18:30 18:30
18:35 18:35
18:40 18:40
18:45 18:45
18:50 18:50
18:55 18:55
19:00 19:00