Current Events

PULSUS warmly welcomes all the participants, Scientists, and Delegates from the globe to join our conference 3rd European Congress on Pharma and Pharmaceutical Sciences during July 24-25, 2019 at Rome, Italy

PULSUS warmly welcomes all the participants, Scientists, and Delegates from the globe to join our conference 3rd European Congress on Pharma and Pharmaceutical Sciences during July 24-25, 2019 at Rome, Italy << less

PULSUS warmly welcomes all the participants, Scientists, and Delegates from the globe to join our conference 3rd European Congress on Pharma and Pharmaceutical Sciences during July 24-25, 2019 at Rome, Italy

PULSUS warmly welcomes all the participants, Scientists, and Delegates from the globe more >>

The aim of the meeting will be to discuss molecular and structural principles of nuclear pore organisation, together with new experimental approaches, mechanisms, and models for nuclear transport. We hope to bring together scientists interested in diverse areas of nuclear pore, transport, lamina, organisation and evolution research to stimulate communication and efficient exchange of experimental results, methodology, concepts, and hypotheses.

Meeting Background
In the past two decades, our understanding of the nuclear envelope (NE) has been radically transformed. From being viewed as a simple membrane barrier with a lamin intermediate filament lining, the NE is now known to incorporate a signaling and regulatory interface as complex and dynamic as that of the plasma membrane. On the outer face of the NE, connections to cytoskeletal filaments direct cell and nuclear migration and mechanosignal transduction, whilst connections to chromatin on its inner face direct genome regulation and stability. The importance of these various roles is highlighted by the association of NE protein mutations with human diseases ranging from muscular dystrophies to neuropathies, lipodystrophies and premature ageing syndromes.

Additionally, emerging technologies are finally enabling the tackling of longstanding questions such as the higher-order structure of the lamin polymer, nuclear membrane synthesis and dynamics, and membrane protein complexes. Many ER proteins are also now being found to contribute to NE dynamics and investigations of pathogen interactions with the NE are yielding yet further insights into this complex structure. This incredible diversity of functions and structure-function relationships underscores the pleiotropy of NE-linked diseases and in this programme we draw upon experts in biophysics, biochemistry, cell biology, microscopy, and virology to highlight the wide breadth of NE functions. By bringing together diverse groups covering a wide range of expertise, from fluorescence fluxuation microscopy to crosslinking mass spectrometry to human genetics, we expect to promote a dialogue that may better elucidate NE disease mechanisms.

Topics:
▪ New directions in nuclear envelopathies
▪ Dynamic nucleo-cytoskeletal interactions and mechanotranduction
▪ Genome regulation from the nuclear envelope
▪ New nuclear envelope signaling pathways and mechanisms
▪ Detailed structure of the lamina and membrane complexes
▪ Nuclear membrane biosynthesis and dynamics
▪ Pathogen interactions with the nuclear membrane


Attendance is through invitation.


REGISTRATION AND PAYMENT

We are arranging the meeting as an ad hoc event, and require a deposit to secure the venue and the prices we have negotiated at eight months prior to the meeting, i.e. 24th January.

Provision rates and what is included are as follows (includes sales tax):

-Single room: £580,

-Double room, single occupancy: £735,

-Double room, double occupancy (accompanying person): £785 (+£160 if joining for dinners).

Please note that the hotel could only reserve 17 single rooms at the lower rate; thus these will have to be distributed either on a first-come-first-serve basis or based on need if a financial case can be made in advance.

The package includes: Five nights accommodation, full board (minus one dinner), coffee/refreshments at breaks and access to full hotel facilities.

Accompanying person in room sharing with paying participant will be entitled to: As participant without attendance at scientific sessions or lunch.

These prices are approximate, and may go down with sponsorship, down more (Brexit) or collapse completely (Brexit).

Additional suppers, lunches and other services can be of course be purchased, as can additional nights at the hotel prior to or after the meeting. These need to be negotiated direct with the hotel, but there is a preferential rate for delegates.

The excursions and gin tasting will be on a pay as you go basis.

Payment deadline is the 31st of May << less

The aim of the meeting will be to discuss molecular and structural principles of nuclear pore organisation, together with new experimental approaches, mechanisms, and models for nuclear transport. We hope to bring together scientists interested in diverse areas of nuclear pore, transport, lamina, organisation more >>

Following the success of the last edition, on behalf of the CDD Press, the Medical Research Council Toxicology Unit we are proud to announce the CDD Conference 2019 on “Cancer, Immunity & Inflammation” which will be held between the 9th and the 11th of September 2019, in Clare College, Cambridge, UK.

The Organisers
Gerry Melino & Ivano Amelio

Confirmed Speakers
Vishva Dixit (San Francisco)
Michael Karin (San Diego)
Tak Mak (Toronto)
Pascal Meier (London)
Andrew Oberst (Seattle)
Klaus Okkenhaug (Cambridge)
Carol Prives (New York)
Yufang Shi (Shanghai)
Ken Smith (Cambridge)
Hans-Uwe Simon (Bern)
Martin Turner (Cambridge)
Peter Vandenabeele (Ghent)
Sally Ward (Southampton)
Xiadong Wang (Beijing)
Ying Wang (Shanghai)
Greg Winter (Cambridge)

Organising Committee
Ivano Amelio (Cambridge)
Gerry Melino (Cambridge)
Anne E. Willis (Cambridge)

CDD MRC-TU Conference Secretariat
Emanuele Panatta & Consuelo Pitolli << less

Following the success of the last edition, on behalf of the CDD Press, the Medical Research Council Toxicology Unit we are proud to announce the CDD Conference 2019 on “Cancer, Immunity & Inflammation” which will be held between the 9th and the 11th of September 2019, in Clare College, Cambridge, more >>

Post-genomic progress in helminth parasitology

Helminth parasites are pervasive pathogens that infect humans, animals and plants worldwide. They impact our agricultural productivity and are a significant cause of morbidity for humans in large parts of the developing world, where they are responsible for eight of the 17 neglected tropical diseases recognized by the WHO. Over the last 10-12 years, helminth parasitology research has been transformed by the appearance of genome, transcriptome, proteome and other “omics” datasets. These in turn have spurred the creation of a suite of functional genomic tools, allowing exploration of the vast amounts of data now available. These tools include RNA interference platforms in several species, while the first applications of CRISPR-based genome editing methods have recently been reported. Meanwhile, large-scale genome sequencing and re-sequencing efforts have proceeded apace, shedding new light on our understanding of evolution on a phylum-wide scale, and on development of anthelmintic resistance mechanisms. This one-day BSP Autumn Symposium aims to highlight some of these exciting research areas, where state-of-the-art technologies are being applied to helminth genome research.
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Post-genomic progress in helminth parasitology

Helminth parasites are pervasive pathogens that infect humans, animals and plants worldwide. They impact our agricultural productivity and are a significant cause of morbidity for humans in large parts of the developing world, where they are responsible more >>

ELRIG is pleased to invite you to the Discovery Technologies meeting.

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BSIR ASM 2019 will take place at Manchester Central on 13th -15th November 2019. Further information : meeting.bsir.org/2019/

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A summit to explore the UK advantage in Cell and Gene Therapy

How can joining up science and value in cell and gene therapy deliver global health impact? The summit will explore the journey from science to patients and what value means for different people and organisations.

This half day event is for scientists, investors and entrepreneurs. Leading women will discuss opportunities and catalyse ideas with the audience. Open to all. << less

A summit to explore the UK advantage in Cell and Gene Therapy

How can joining up science and value in cell and gene therapy deliver global health impact? The summit will explore the journey from science to patients and what value means for different people and organisations.

This half more >>