Current Events

We are organizing “5th International Conference on Vascular Biology & Surgeons Meeting” during February 25-26,2019 at London, UK.

Vascular Conference 2019 highlights the theme " Exploring the Advancements in Vascular Biology with Surgeons". Vascular Conference 2019 is an event intended to provide an exclusive platform for new researchers, scholars, cardiologists, doctors, vascular surgeons, physicians, students and Residents and General Surgeons, Angiology Specialists, Phlebologists, Interventional Radiologists, Vascular Medicine Specialists, Dermatologists, Nurses, Technicians and all others interested in the management. You can avail a group discount on attending the conference and credits will be given to all the attendees.
For more details: https://vascular.cmesociety.com/
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We are organizing “5th International Conference on Vascular Biology & Surgeons Meeting” during February 25-26,2019 at London, UK.

Vascular Conference 2019 highlights the theme " Exploring the Advancements in Vascular Biology with Surgeons". Vascular Conference 2019 is an event intended to provide more >>

18th Pharmacovigilance 2019
27th & 28th February 2019, Pestana Chelsea Bridge Hotel, London, UK
18th Annual Pharmacovigilance 2019 will bring together top pharmaceutical, biotechnology and regulatory representatives under one roof that will address the key issues of the industry. The entire program will cover the detection, analysis and prevention of adverse drug reactions. This conference will help the drug safety representatives from the pharmaceutical industry and academic and quality research organizations who wish to understand how to avoid common deficiencies in inspections by learning from the experiences of others; to gain a greater understanding of new and existing pharmacovigilance requirements, and to improve their organization’s compliance with pharmacovigilance requirements. Hence, this conference will provide an important platform for pharmacovigilance stakeholders to discuss and share best practices in expediting pharmacovigilance development.
SPONSORS:
• Gold Sponsor: APCER LIFE SCIENCES
• Bronze Sponsor: BROOKWOOD, Pharma Solutions Internation GmbH
KEY SPEAKERS:
• JACKIE ROBERTS, Executive Director Regulatory, Pharmacovigilance and Medical / QPPV, Accord Healthcare
• JABEEN AHMAD, Regional PV Director, EEMEA, Abbvie
• SUSAN WELSH, Chief Safety Officer, CSL Behring (USA)
• RICARDA TIEMEYER, Head of Drug Safety & PoC Medical Information, Roche
• PAOLO VOLTOLINA, Associate Director Regulatory Affairs, CSL Behring
• MIROSLAVA NOVAKOVA, Medical Advisor, Sanofi Pasteur (Slovak Republic)
• YUUNG YUUNG YAP, Senior International Regulatory Counsel, EU and International Regulatory Law, Pfizer
• DAVID JEFFERYS, Sr. VP Regulatory, Eisai
• TANJA PETERS, Global Head of PV Intelligence, Deputy EU QPPV, Boehringer Ingelheim
• JOHN SOLOMON, Head of Pharmacovigilance - UK & Ireland, Sanofi
• SUMIT MUNJAL, Global Director, Pharmacovigilance & EU Region Medical Advisor - Lead Oncology Portfolio, Takeda Pharmaceuticals
• MICHAEL BEAN, Senior Director, Regulatory Compliance R&D, Johnson & Johnson
• STEINAR MADSEN, Medical Director, Norweigen Medicines Agency
• PAUL WANG, Director, Safety Science, Kite Pharma (USA)
• DORIS STENVER, Chief Medical Officer, Member of the Pharmacovigilance Risk Assessment Committee (PRAC), Danish Medicines Agency
• ALEJANDRA PADOVANI, Safety Scientist, Roche
• SABINE POLTERMANN, Head Scientific Product Information, Novartis
• HEINZ WEIDENTHALER, Director Pharmacovigilance, QPPV, Bavarian Nordic
• MIRCEA CIUCA, Global Head Medical & Clinical Drug Safety, Vifor Pharma
• FRANCK SCHWARTZ, QA Global Inspection, Intelligence Lead - Compliance and Regulatory Affairs, Novartis
• ALINA TUDOR, Associate Director, Senior PV Physician/Deputy EUQPPV, Norgine
• RAJ BHOGAL, Safety & International Director, Regulatory Inspections, R&D QA&C, Shire Pharmaceuticals
Plus many more
KEY THEMES:
• Brexit Implications for the UK Pharmaceutical (pharmacovigilance) Industry
• What would 'no deal' mean for medicine?
• New Technologies in Pharmacovigilance (AI/ Machine Learning, IoT)
• Quality, Safety and Signal Detection - Future of 2020
• PV Audit & Inspections – Knowing what is to be done
• Drug safety work in the pre-clinical/clinical transition and early clinical development phase
• Pharmacovigilance in 2020 - future horizons and efficiencies
• Updates towards of legislation, policies, systems, technology, communication strategies and best practice in PV
• Possible effects of Brexit on Pharmacovigilance
• Benefit/Risk ratio: the common denominator
• Market analysis – What is our current stand? – Moving towards the new successful PV era
• PV – Risk Management and Planning
• Risk management in the lifecycle of a drug
• Examining developments in GVP measures and status of the new Module VI
• Improving in signal management and their implications
• Latest updates and hot topics relating to the role of the QPPV
• Challenges and Opportunities to optimize the overall PV ecosystem for maximum benefit
• Quality, Safety and Signal Detection - Future of 2020
• Medical devices – Increasing safety perspective
• Case studies from various countries on the PV frameworks around the world
• Good Clinical Practices and Good Pharmacovigilance practices
• Proper communication - Sponsor – Site – CRO & Patients
• Patient centric approach to help improve patient safety
• Outsourcing activities - How to set it right?
• How to involve patients better to develop drugs
• The developing regulatory framework in advanced and developing markets – EU, USA & ROW
• Accelerating new medicine introduction in developing world & overcoming challenges
• Be part of a major networking opportunity
WHO SHOULD ATTEND:
CEO’s, CTO’s, CIO’s, Presidents, VPs, Directors, Heads, Managers, Scientific Advisors, Consultants of:
Pharmacovigilance, Pharmacoepidemiology, Pharmacogenomics, Drug/Product Safety, Drug Development, Information and Clinical Data Management, Clinical Pharmacology, Clinical Safety, Periodical safety update Reports, Risk Management, Research & Development, Quality Assurance, Patient Safety, Signal Detection, Safety Surveillance, Outcomes Research, Data Analysis, Epidemiology, Medical Affairs, Regulatory Affairs and Compliance, Information technology, Sales and Marketing
CONFERENCE SPONSORSHIP:
Email: kavitha@virtueinsight.co.in or TEL: +44 2036120886
Sponsor, Exhibition Stall (Booth) and a paid Speaker Slots are also available
We also have some sponsorship opportunities available for the event, which gives you an opportunity to sponsor/speak/exhibit, and create brand awareness. In addition, the networking opportunities in focused and relevant industry gathering provide the personal contact necessary for business development efforts.
CONFERENCE REGISTRATION:
Email: kavitha@virtueinsight.co.in or TEL: +44 2036120886
• Introductory Offer (3 delegate places for the price of 2) - A huge saving discount and only Limited seats left.
• Early Bird Discount (Ends 17th January 2019): Conference Delegate Pass (£950 + VAT per delegate)
• Standard Registration (From 19th January 2019): Conference Delegate Pass (£1150 + VAT per delegate)
Get more from the event, with a broader scope bringing the whole communications value chain together. Enjoy and make the best out of our dedicated networking drinks time, meet the leading international vendors showcasing the products of tomorrow in the co-located exhibition. Expand your knowledge of the latest business models and strategies in the high-level conference.


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18th Pharmacovigilance 2019
27th & 28th February 2019, Pestana Chelsea Bridge Hotel, London, UK
18th Annual Pharmacovigilance 2019 will bring together top pharmaceutical, biotechnology and regulatory representatives under one roof that will address the key issues of the industry. The entire program more >>

The inaugural ELRIG CRISPR in Drug Discovery: From Targets to Therapeutics meeting will be held at the King’s Centre, Oxford 27-28 February 2019. Genome Engineering, including Zinc-finger, TALEN and most recently CRISPR/Cas9, has become a powerful tool in the drug discovery pipeline. This meeting will focus on the application of genome engineering to identify novel drug targets through large scale CRISPR based functional genomics studies, target validation in developing advanced cellular and in vivo disease models, and the pioneering applications in therapeutic genome editing. A current perspective of the applications of these rapidly developing technologies with a focus on drug discovery applications will be the meeting’s focus. << less

The inaugural ELRIG CRISPR in Drug Discovery: From Targets to Therapeutics meeting will be held at the King’s Centre, Oxford 27-28 February 2019. Genome Engineering, including Zinc-finger, TALEN and most recently CRISPR/Cas9, has become a powerful tool in the drug discovery pipeline. This meeting will more >>

On behalf of the Diabetes 2019 , it gives us an immense pleasure to invite you all to the "International Conference on Diabetes, Hypertension and Metabolic Syndrome" scheduled during March 7-8, 2019 at London, UK with a theme, “New insights in prevention and management of diabetes through intervening technologies”.

Diabetes 2019 will provide a great opportunity beyond any comparison to attend and network with Diabetes Community.

Networking activities to facilitate the exchange of information and encourage the development of research.

This occasion gives an ideal stage to driving researchers, specialists, researchers, professionals, medicinal services specialists, treatment suppliers, hardware and analytic apparatuses makers/sellers, to pick up learning about the most recent progressions in clinical research and health diagnostics inside the separate field and supports new advancements, look into thoughts around the world.

Target Audience:

· Endocrinology & Diabetes students, Scientists

· Endocrinology & Diabetes Researchers

· Endocrinology & Diabetes Faculty

· Medical Colleges

· Endocrinology & Diabetes Associations and Societies

· Business Entrepreneurs

· Manufacturing Medical Devices Companies

· Hypertension Societies and Associations

· Hypertension or Cardiology and related departments

· Hypertension institutes

· Training Institutes

· Research students

· Pharma Companies << less

On behalf of the Diabetes 2019 , it gives us an immense pleasure to invite you all to the "International Conference on Diabetes, Hypertension and Metabolic Syndrome" scheduled during March 7-8, 2019 at London, UK with a theme, “New insights in prevention and management of diabetes through intervening more >>

2nd Annual Pharma Regulatory Summit 2019
14th March 2019, Kohinoor Continental Hotel, Mumbai, India
I’m happy to invite you to our 2nd Annual Pharma Regulatory Summit 2019 to attend as a sponsor/delegate to be held on 14th March 2019, Kohinoor Continental Hotel, Mumbai, India.
This Pharma Regulatory Summit is the leading platform for regulatory experts, to be updated with latest country updates and strategies to navigate the complex and ever changing regulations in the region. This conference will focus on the new strategies, amendments, innovations, developments in the fields of regulatory affairs, intellectual property and medical devices, which reflects new strategies in the field of regulatory affairs. Regulatory Affairs additionally have certain significance inside the Healthcare industries, such as pharmaceuticals, medical devices, biologics and practical nourishments.
KEY SPEAKERS:
• RAMKISHAN, Deputy Drugs Controller, DDC(I), CDSCO
• RAJENDRA SANGHAVI, Sr. Consulting Clinician & Chairman - Medical Committee, Indian Drug Manufacturers’ Association (IDMA)
• V. KALAISELVAN, Principal Scientific Officer, Indian Pharmacopoeia Commission
• MAYUR PARMAR, Deputy Collector, Government Of Gujarat
• KETAN KOTADIYA, Associate Director- Regulatory Affairs, Merck Sharp & Dohme
• SHANTANU MUKHERJEE, Legal Head, Asia Pacific and Japan, Lupin
• OMPRAKASH S. SADHWANI, Former Joint Commissioner and controlling Authority, Food and Drug Administration (Maharashtra state)
• KEDAR SUVARNAPATHAKI, Head - Regulatory Affairs & IP, Boehringer Ingelheim
• AMITA BHAVE, Head Regulatory Affairs GDD India, Novartis
• RAJESH NAIK, Head Medical Affairs Oncology, Boehringer Ingelheim
• ALAP GANDHI, Head, Medical Affairs, GSK
• RITU JOHARI, Head-Scientific Affairs, Quality & Regulatory, Abbott Diabetes Care
• MILIND NARVEKAR, Head Regulatory Affairs, Apotex Research
• S.R.SALUNKHE, Former Assistant commissioner, FDA Maharashtra
• PRATIK SHAH, (Former Head - Clinical, Medical & Regulatory Affairs, PV and QA Astellas Pharma), Independent Consultant
• VIJAYA ANAND, Chief Manager - Corporate Regulatory Affairs, Piramal
• NISHA FERNANDES, Manager - Regulatory Affairs, Amgen
• HITENDRA BHATIA, Independent Consultant – Regulatory Affairs
WHO SHOULD ATTEND:
This conference is specifically designed for pharma, biotech, CRO’s, Government and Regulators, Hospitals/Trial Sites, Technology & Solution Providers and med device professionals responsible for
Regulatory Affairs, Regulatory Writing, Medical Writing, Publishing, Information, Submissions, Document and eRecords Management, Business Operations, Processing, Labelling, Clinical Trials Management, Data, Clinical Data, Outsourcing, Clinical Outsourcing, Vendor Management, Product Development, Quality Assurance, Quality Control
CONFERENCE SPONSORSHIP:
E-mail - kavitha@virtueinsight.co.in Tel: +9144 24762472
Sponsor, Exhibition Stall (Booth) and a paid Speaker Slots are also available
We also have some sponsorship opportunities available for the event, which gives you an opportunity to sponsor/speak/exhibit, and create brand awareness. In addition, the networking opportunities in focused and relevant industry gathering provide the personal contact necessary for business development efforts.
CONFERENCE REGISTRATION PROCESS:
E-mail - kavitha@virtueinsight.co.in Tel: +9144 24762472
• Early Bird Discount Price (Ends 28th January 2019) – (INR 10,000 + GST (18%) per delegate)
• Standard Price (From 29th January 2019 Onwards) – (INR 15,000 + GST (18%) per delegate)
In order to register you can simply e-mail me your invoice details in the below mentioned format;
• Name:
• Company Name & Address:
• GST Number:
• Job Position:
• Contact Number:
Get more from the event, with a broader scope bringing the whole communications value chain together. Enjoy and make the best out of our dedicated networking drinks time, meet the leading international vendors showcasing the products of tomorrow in the co-located exhibition. Expand your knowledge of the latest business models and strategies in the high-level conference.

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2nd Annual Pharma Regulatory Summit 2019
14th March 2019, Kohinoor Continental Hotel, Mumbai, India
I’m happy to invite you to our 2nd Annual Pharma Regulatory Summit 2019 to attend as a sponsor/delegate to be held on 14th March 2019, Kohinoor Continental Hotel, Mumbai, India.
This Pharma more >>

Innovations to Drive Future Drug Discovery

Conference Directors: Darren Cawkill (Apollo Therapeutics) & Jon Hutchinson (GlaxoSmithKline)

Plenary Keynote Speakers: Professor Steve Jackson (University of Cambridge) & Harren Jhoti (Astex Pharmaceuticals)

New biology continues to emerge at a fast pace and is revealing many new and exciting therapeutic opportunities for drug discovery scientists; potential novel drug targets and new mechanisms-of-action. It is critical that the drug discovery field continually adapts and equips with new technologies and innovations that will enable targets to be prosecuted no matter which direction the cutting-edge biology has taken. Hence the 2019 ELRIG R&I conference will discuss how the most promising new biology is being identified and discovered and seek to explore what promising new technologies and innovations are emerging to enable this science to be effectively translated into successful therapeutics. << less

Innovations to Drive Future Drug Discovery

Conference Directors: Darren Cawkill (Apollo Therapeutics) & Jon Hutchinson (GlaxoSmithKline)

Plenary Keynote Speakers: Professor Steve Jackson (University of Cambridge) & Harren Jhoti (Astex Pharmaceuticals)

New biology continues to emerge more >>

to the upcoming 4th International conference on Food Science & Technology during April 08-09, 2019 at Zurich, Switzerland. The main theme of the conference is " Reconnoiter the Prodigious Advancements in the Bailiwicks of Food Science & Technology " which covers a broad array of vitally key sessions.
Based on your expertise and research work on Food Science, we would like to honor you by inviting you to the position of Organizing Committee Member for Food Technology 2019. Also we would like to invite you as a plenary speaker at our conference, which was a highest privilege we can offer towards your participation at our conference.
As an Organizing Committee Member the privileges would include a position as the chair/co-chair for the session of your interest.
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to the upcoming 4th International conference on Food Science & Technology during April 08-09, 2019 at Zurich, Switzerland. The main theme of the conference is " Reconnoiter the Prodigious Advancements in the Bailiwicks of Food Science & Technology " which covers a broad array of vitally key sessions.
Based more >>

AAC welcome you to attend 2nd International Conference on Laser, Optics and Photonics during April 15-16, 2019 at Frankfurt, Germany. Laser Tech 2019 hits the floor of Frankfurt with the theme: Share the Vision to Shape the Future of Laser, Optics and Photonics. The premier conference for the latest developments including Semiconductor Lasers, Laser Medical technologies, Active Optical Sensing, Nonlinear Optical Technologies, Nano-Optics and Plasmonics, Quantum Photonics, Nanophotonics, Advanced Laser Processing. Attend the conference to mark your ideas before the esteemed personalities.

Website Details: http://laser-tech.alliedacademies.com/

Regards and Thanks,
Luna Emilia
Program Manager | Laser Tech 2019
Contact No: +44-203-769-1755
Mail id: lasertech@alliedconference.org << less

AAC welcome you to attend 2nd International Conference on Laser, Optics and Photonics during April 15-16, 2019 at Frankfurt, Germany. Laser Tech 2019 hits the floor of Frankfurt with the theme: Share the Vision to Shape the Future of Laser, Optics and Photonics. The premier conference for the latest more >>

4th International Conference on Applied Physics
April 15-16, 2019 | Frankfurt, Germany

Theme: ‘A Step into the Future, Recent Progress and Innovations in Physics’
The pioneers in modern science and technology conferences, back again to revolutionize the future of next generation technologies. Physics Conference 2019 lays a platform for the researching community and industrial institutes to gather and form a network to present their research works and expertise on April 15-16, 2019 at Frankfurt, Germany.
This year the Physics meeting enables the delegates and students to comprehend the recent discoveries, innovations and technologies from researchers in diverse fields and have a deep knowledge on the impacts of these technologies in the future. Physics Conference 2019 provides an opportunity to connect with the leading scientists and researchers in the field of Physics.
Reasons to attend:
• Meet Experts & Influencers Face to Face
• Publishing your research works
• Position yourself as a leading researcher and technological expert
• Networking with peers from different arenas
• New Tips & Tactics to enhance your research works
• Encounter new vendors and suppliers
• The Energy of Like-Minded Individuals
• The Serendipity of the Random Workshop
Join us at Physics 2019, the technological forum that connects the distinguished industrialists and academicians all over the world in the field of Physics, Acoustics, Laser Optics, Photonics and Photovoltaics, Medical Physics, Clinical Imaging, Quantum Physics, Nanotechnology, Biophysics, Materials Science, Microscopy, Astronomy, Mathematics, Energy Physics and more.
For more details regarding this event visit Physics 2019 Webpage: http://physics.alliedacademies.com/
Organizer Details:
Fiona Davies
Program Manager | Physics 2019
47 Churchfield Road,
London W36AY, UK
Tel: +44 203 769 1755
E-mail: physics@alliedconference.org
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4th International Conference on Applied Physics
April 15-16, 2019 | Frankfurt, Germany

Theme: ‘A Step into the Future, Recent Progress and Innovations in Physics’
The pioneers in modern science and technology conferences, back again to revolutionize the future of next generation technologies. more >>

The 2019 Spring Meeting will be held at Manchester University on 15-17 April. The local organisers are Dr Ilaria Russo and Prof Kathryn Else, working with Prof Geoff Hide, Prof Guy Caljon, Prof Ron Hokke and Dr Erinma Ochu.

Keynote speakers include: Prof Joanne Webster (Royal Veterinary College) and Prof Patricia Wright (Stoneybrook, USA) for One Health and Prof Andy Miah (Salford) for Science Communication.

Dateline:

Abstract submission : open Closes March 2019
Ticketing: opens October 2018
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The 2019 Spring Meeting will be held at Manchester University on 15-17 April. The local organisers are Dr Ilaria Russo and Prof Kathryn Else, working with Prof Geoff Hide, Prof Guy Caljon, Prof Ron Hokke and Dr Erinma Ochu.

Keynote speakers include: Prof Joanne Webster (Royal Veterinary College) more >>

The EE & RE exhibition is a platform for many local and foreign companies to showcase their eco-friendly solutions for energy production and consumption. The event has the format “exhibition-conference” and is open to visitors from the sectors of automation, energy, construction, engineering, different industry branches, representatives of municipalities and government administration, HVAC, lighting, transport and logistics, etc.

The program for the parallel conference will become available on the event website by the end of the year.

Presented solutions: • Energy efficient heating and cooling systems - heat pumps, biomass boilers • Cogeneration plants • Energy from waste • Biogas plants for the food industry and agriculture, waste-water treatment plants • Energy management, audit and consulting • LED lighting • Photovoltaic panels, hybrid systems for autonomous power supply • Equipment for heating, air-conditioning and gas installations • Systems for the production of pellets from wood, straw, sunflower husks, municipal/household waste, etc. << less

The EE & RE exhibition is a platform for many local and foreign companies to showcase their eco-friendly solutions for energy production and consumption. The event has the format “exhibition-conference” and is open to visitors from the sectors of automation, energy, construction, engineering, different more >>

The Save the Planet exhibition showcases local and foreign companies, who offer products and solutions for waste collection, treatment and utilization. A conference on the same topics will take place parallel to the exhibition. The event is open to representatives of municipalities and government administration, ecologists, investors, managers of companies from the sectors recycling, waste management, agriculture, food and packaging, etc.

The program for the parallel conference will become available on the event website by the end of the year.

Exhibitors profile: Waste management; Waste collection; Transport vehicles and technologies; Waste treatment equipment; Medical waste treatment and disposal; Landfill; Waste-to-Energy; Thermal treatment - by direct combustion; Recycling; Plants for recycling; Services
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The Save the Planet exhibition showcases local and foreign companies, who offer products and solutions for waste collection, treatment and utilization. A conference on the same topics will take place parallel to the exhibition. The event is open to representatives of municipalities and government administration, more >>

Smart Cities aims to popularize modern technologies and practices that can turn our cities into more eco-friendly and effective systems. It is a meeting point for solution providers and consumers. The parallel conference offers a chance to obtain information on current trends, legislation and perspectives. Among the event participants are companies offering solutions for passive houses, public transport innovations, energy efficient lighting, software for smart buildings and industry, etc.

The program for the parallel conference will become available on the event website by the end of the year.

Exhibitors Smart Cities:

• Energy Efficiency in Smart Cities and Smart Buildings;
• Sustainable City Mobility;
• Information and Communication Technologies (ICT) for Smart Cities;
• Smart Energy;
• Sustainable City Environment
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Smart Cities aims to popularize modern technologies and practices that can turn our cities into more eco-friendly and effective systems. It is a meeting point for solution providers and consumers. The parallel conference offers a chance to obtain information on current trends, legislation and perspectives. more >>

Conference Series llc Ltd takes immense pleasure & feels honoured in inviting the contributors across the globe to attend “17th International Pharmaceutical Microbiology and Biotechnology Conference” to be held during April 29-30, 2019 at London, UK on the theme " explore the development of research in the field of microbiology " which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions. << less

Conference Series llc Ltd takes immense pleasure & feels honoured in inviting the contributors across the globe to attend “17th International Pharmaceutical Microbiology and Biotechnology Conference” to be held during April 29-30, 2019 at London, UK on the theme " explore the development of research more >>

The third ELRIG meeting on Advances in Cell Based Profiling in Drug Discovery will be held on the 22nd and 23rd of May 2019 at the AstraZeneca R&D premises in Gothenburg. This interactive 2-day event will host leading scientists from academia and industry to discuss current and future formats for cell based assays. This time the bi-annual meeting will be accompanied by a satellite meeting on Chemical Biology on May 24th, organized by key academic infrastructures in the Nordic countries. Our aim is to create an open and inspiring environment for networking between biologists and chemists, working towards a common view on expectations from our cell assays and their use for target identification, target validation and compound profiling purposes. << less

The third ELRIG meeting on Advances in Cell Based Profiling in Drug Discovery will be held on the 22nd and 23rd of May 2019 at the AstraZeneca R&D premises in Gothenburg. This interactive 2-day event will host leading scientists from academia and industry to discuss current and future formats for cell more >>

The aim of the meeting will be to discuss molecular and structural principles of nuclear pore organisation, together with new experimental approaches, mechanisms, and models for nuclear transport. We hope to bring together scientists interested in diverse areas of nuclear pore, transport, lamina, organisation and evolution research to stimulate communication and efficient exchange of experimental results, methodology, concepts, and hypotheses.

Meeting Background
In the past two decades, our understanding of the nuclear envelope (NE) has been radically transformed. From being viewed as a simple membrane barrier with a lamin intermediate filament lining, the NE is now known to incorporate a signaling and regulatory interface as complex and dynamic as that of the plasma membrane. On the outer face of the NE, connections to cytoskeletal filaments direct cell and nuclear migration and mechanosignal transduction, whilst connections to chromatin on its inner face direct genome regulation and stability. The importance of these various roles is highlighted by the association of NE protein mutations with human diseases ranging from muscular dystrophies to neuropathies, lipodystrophies and premature ageing syndromes.

Additionally, emerging technologies are finally enabling the tackling of longstanding questions such as the higher-order structure of the lamin polymer, nuclear membrane synthesis and dynamics, and membrane protein complexes. Many ER proteins are also now being found to contribute to NE dynamics and investigations of pathogen interactions with the NE are yielding yet further insights into this complex structure. This incredible diversity of functions and structure-function relationships underscores the pleiotropy of NE-linked diseases and in this programme we draw upon experts in biophysics, biochemistry, cell biology, microscopy, and virology to highlight the wide breadth of NE functions. By bringing together diverse groups covering a wide range of expertise, from fluorescence fluxuation microscopy to crosslinking mass spectrometry to human genetics, we expect to promote a dialogue that may better elucidate NE disease mechanisms.

Topics:
▪ New directions in nuclear envelopathies
▪ Dynamic nucleo-cytoskeletal interactions and mechanotranduction
▪ Genome regulation from the nuclear envelope
▪ New nuclear envelope signaling pathways and mechanisms
▪ Detailed structure of the lamina and membrane complexes
▪ Nuclear membrane biosynthesis and dynamics
▪ Pathogen interactions with the nuclear membrane


Attendance is through invitation.


REGISTRATION AND PAYMENT

We are arranging the meeting as an ad hoc event, and require a deposit to secure the venue and the prices we have negotiated at eight months prior to the meeting, i.e. 24th January.

Provision rates and what is included are as follows (includes sales tax):

-Single room: £580,

-Double room, single occupancy: £735,

-Double room, double occupancy (accompanying person): £785 (+£160 if joining for dinners).

Please note that the hotel could only reserve 17 single rooms at the lower rate; thus these will have to be distributed either on a first-come-first-serve basis or based on need if a financial case can be made in advance.

The package includes: Five nights accommodation, full board (minus one dinner), coffee/refreshments at breaks and access to full hotel facilities.

Accompanying person in room sharing with paying participant will be entitled to: As participant without attendance at scientific sessions or lunch.

These prices are approximate, and may go down with sponsorship, down more (Brexit) or collapse completely (Brexit).

Additional suppers, lunches and other services can be of course be purchased, as can additional nights at the hotel prior to or after the meeting. These need to be negotiated direct with the hotel, but there is a preferential rate for delegates.

The excursions and gin tasting will be on a pay as you go basis.

Payment deadline is the 31st of May << less

The aim of the meeting will be to discuss molecular and structural principles of nuclear pore organisation, together with new experimental approaches, mechanisms, and models for nuclear transport. We hope to bring together scientists interested in diverse areas of nuclear pore, transport, lamina, organisation more >>

ELRIG is pleased to invite you to the Discovery Technologies meeting.

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