Profile of Prof Paul Kaye
Overview
Antigen presentation
Dendritic cells
Imaging
Immunopathology
Inflammation
Leishmaniasis
Macrophages
Paul's laboratory continues to focus on the immunopathology of leishmaniasis, with emphasis both on exploring opportunities for developing novel host-directed therapies and also for gaining new insight into myeloid cell function. Ongoing projects span fundamental research into macrophage and dendritic cell development, heterogeneity and function, studies on the immunological determinants of transmission to sand flies, research on human immunopathology, and clinical trials of a new vaccine for leishmaniasis. His research group has active collaborations in Brazil, India, Sri Lanka and across East Africa.