Thursday 26 September
Discussion Keynote Chair Plenary Keynote Forum /
Workshop
Exhibitor
[Schedule with Tracks only]
DAY 1The AuditoriumHelix Room 1Helix Room 2DAY 1
DAY 1The AuditoriumHelix Room 1Helix Room 2DAY 1
08:00 Arrival, registration & welcome coffee 08:00
08:05 08:05
08:10 08:10
08:15 08:15
08:20 08:20
08:25 08:25
08:30 08:30
08:35 08:35
08:40 08:40
08:45 08:45
08:50 08:50
08:55 08:55
09:00 Conference Introduction 09:00
09:05 09:05
09:10 Plenary Keynote
Widening the Therapeutic Window: Kinetic Selectivity and Target Vulnerability
09:10 (45 mins)
Prof Peter Tonge, Stony Brook University 
09:10
09:15 09:15
09:20 09:20
09:25 09:25
09:30 09:30
09:35 09:35
09:40 09:40
09:45 09:45
09:50 09:50
09:55 09:55
10:00 Session Chair Introductions Session Chair Introductions Session Chair Introductions 10:00
10:05 Imaging techniques in Drug Discovery
Functional ultrasound - novel in-vivo imaging technique for pre-clinical CNS drug discovery
10:05 (30 mins)
Antti Nurmi , Charles River Discovery Services Finland 
Approaches for early safety assessment
SNPing in and out of stem cell-cardiomyocytes with Cas9/CRISPR
10:05 (30 mins)
Prof Chris Denning, University of Nottingham 
Enzymology in Drug Discovery
Getting in a Flap with DNA
10:05 (30 mins)
Prof Jane Grasby, University of Sheffield 
10:05
10:10 10:10
10:15 10:15
10:20 10:20
10:25 10:25
10:30 10:30
10:35 Technology Spotlight Presentations Technology Spotlight Presentations Technology Spotlight Presentations 10:35
10:40 10:40
10:45 Coffee Break 10:45
10:50 10:50
10:55 10:55
11:00 11:00
11:05 11:05
11:10 11:10
11:15 11:15
11:20 11:20
11:25 11:25
11:30 Imaging techniques in Drug Discovery
Techniques for multiscale fluorescence imaging of 3D in vitro models
11:30 (30 mins)
Mike Shaw, The National Physical Laboratory  
Approaches for early safety assessment
TBC
11:30 (30 mins)
Paul Walker, Cyprotex 
Enzymology in Drug Discovery
TBC
11:30 (30 mins)
Gareth Davies, AstraZeneca 
11:30
11:35 11:35
11:40 11:40
11:45 11:45
11:50 11:50
11:55 11:55
12:00 Imaging techniques in Drug Discovery Approaches for early safety assessment
TBC
12:00 (30 mins)
Nigel Greene, AstraZeneca 
Enzymology in Drug Discovery
The rise of high-throughput mass spectrometry for cellular profiling of early drug candidates
12:00 (30 mins)
Martin Bachman, Medicines Discovery Catapult 
12:00
12:05 12:05
12:10 12:10
12:15 12:15
12:20 12:20
12:25 12:25
12:30 Technology Spotlight Presentations Technology Spotlight Presentations Technology Spotlight Presentations 12:30
12:35 Poster Spotlight Presentations Poster Spotlight Presentations Poster Spotlight Presentations 12:35
12:40 12:40
12:45 12:45
12:50 12:50
12:55 12:55
13:00 Lunch 13:00
13:05 13:05
13:10 13:10
13:15 13:15
13:20 13:20
13:25 13:25
13:30 13:30
13:35 13:35
13:40 13:40
13:45 13:45
13:50 13:50
13:55 13:55
14:00 14:00
14:05 14:05
14:10 14:10
14:15 14:15
14:20 14:20
14:25 14:25
14:30 Imaging techniques in Drug Discovery
High content 3-D light sheet microscopy in 96 and 384-well plate formats: cancer cell morphology and invasiveness and spheroid-based assays for compound safety screening
14:30 (30 mins)
Christopher Dunsby, Imperial College, London 

Multimodal, Multiscale Imaging in Drug Discovery
15:00 (30 mins)
Dr Philippa Hart, Medicines Discovery Catapult 
Approaches for early safety assessment Enzymology in Drug Discovery
Biophysical analysis of tethered enzymatic reactions in surface plasmon resonance with application to the tyrosine phosphatase SHP-1
14:30 (30 mins)
Omer Dushek, University of Oxford 

Mechanics and execution of homologous recombination: a single-molecule view
15:00 (30 mins)
Ondrej Belan, Francis Crick Institute 
14:30
14:35 14:35
14:40 14:40
14:45 14:45
14:50 14:50
14:55 14:55
15:00 15:00
15:05 15:05
15:10 15:10
15:15 15:15
15:20 15:20
15:25 15:25
15:30 Coffee Break 15:30
15:35 15:35
15:40 15:40
15:45 15:45
15:50 15:50
15:55 15:55
16:00 Imaging techniques in Drug Discovery
Preclinical imaging technologies for assessing drug toxicity and cancer treatment response
16:00 (30 mins)
Dr Harish Poptani, University of Liverpool 
Approaches for early safety assessment
New Models for Human-relevant ADMET Investigations
16:00 (30 mins)
Prof Ian Wilson, Imperial College London 
Enzymology in Drug Discovery
TBC
16:00 (30 mins)
Steven Charlton, Nottingham Univ. 
16:00
16:05 16:05
16:10 16:10
16:15 16:15
16:20 16:20
16:25 16:25
16:30 Conference close 16:30
16:35 16:35
16:40 16:40
16:45 16:45
16:50 16:50
16:55 16:55
17:00 17:00
17:05 17:05
17:10 17:10
17:15 17:15
17:20 17:20
17:25 17:25
17:30 17:30
17:35 17:35
17:40 17:40
17:45 17:45
17:50 17:50
17:55 17:55
18:00 18:00