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Discussion
Thursday 13 October
14 October
DAY 1ROOM 3HALL 1CHALL 1BRoom 11ARoom 11C
DAY 2
All times shown are GMT —
DAY 1ROOM 3HALL 1CHALL 1BRoom 11ARoom 11C
DAY 2
08:00 Arrival, Registration & Coffee 08:00
08:05 08:05
08:10 08:10
08:15 08:15
08:20 08:20
08:25 08:25
08:30 08:30
08:35 08:35
08:40 08:40
08:45 How can we build a new drug discovery ecosystem, which will complement Boston?
08:45 (45 mins)
Chas Bountra, Oxford SGC - University of Oxford  
Please go to Plenary Keynote Room 3 Prof Chas Bountra, Oxford SGC - University of Oxford
Please go to Plenary Keynote Room 3 Prof Chas Bountra, Oxford SGC - University of Oxford
Genedata AG
Genedata Workshop: Modern Screening Data Analysis:Mastering Biological, Technical and Collaborative Complexity...[More]
2016-10-13 08:45:002016-10-13 09:30:00Europe/LondonGenedata AGSession at 10th Anniversary Drug Discovery 2016 https://www.myeventflo.com/eventflo.asp?evID=1918OnlineSanj Kumar, ELRIGinfo@elrig.org
08:45
08:50 08:50
08:55 08:55
09:00 09:00
09:05 09:05
09:10 09:10
09:15 09:15
09:20 09:20
09:25 09:25
09:30 Chair Intro: Innovations in Chemistry Session
Chairs: Simon Ward, University of Sussex  Ed Tate, Imperial College London  
Chair Intro: Translational & Predictive Models Session
Chairs: Malcolm Haddrick, AstraZeneca  Veronique Birault, Crick Institute  
Oncology & Immunology Session
Chairs: Namir Hassan, Immunocore  David Gilham, Manchester Cancer Research Centre  
Welcome and Introduction. Speaker - Stephan Heyse, Genedata
Labcyte Inc.
Labcyte Workshop - Introduction to TRACK 1...[More]
2016-10-13 09:30:002016-10-13 09:45:00Europe/LondonLabcyte Inc.Session at 10th Anniversary Drug Discovery 2016 https://www.myeventflo.com/eventflo.asp?evID=1918OnlineSanj Kumar, ELRIGinfo@elrig.org
09:30
09:35 09:35
09:40 A foundation in the murky waters of Discovery: Layering a platform across piles of in-vitro screens. Speaker - Margarita Shatalina, Genedata
09:40
09:45 Sugars and Proteins
09:45 (45 mins)
Keynote Speaker: Ben Davis, Oxford University  
Small Cell Lung Cancer Circulating Tumour Cell-Derived Explants - A New Preclinical Platform for Examining Drug Response
09:45 (45 mins)
Keynote Speaker: Kris Frese , Manchester University  
Immuno-oncology:harnessing the immune system to combat cancer
09:45 (45 mins)
Keynote Speaker: Robert Wilkinson, Medimmune  
Automated Acoustic Dispensing:Clinic and Research. Speaker - Kristin Blom, University Hospital Uppsala, Sweden
09:45
09:50 09:50
09:55 09:55
10:00 Integrating screening data across a large multisite pharma organization. Speaker - Dave Murray, AstraZeneca
10:00
10:05 10:05
10:10 10:10
10:15 10:15
10:20 Targeting Individual Cancers Using Chemical Systems Medicine. Speaker - Krister Wennerberg, Institute of Molecular Medicine, Finland
10:20
10:25 10:25
10:30 Specific Correction of Alternative Survival Motor Neuron 2 (SMN2) Splicing by Small Molecules: Discovery of a Potential Novel Medicine to Treat Spinal Muscular Atrophy
10:30 (30 mins)
Hasane Ratni, Roche  
Chip-Based Microphysiological Systems and Drug Discovery
10:30 (30 mins)
Uwe Marxx, TissUse  
Biomarker Strategy to Guide Clinical Development of ImmTACTM molecules, a Novel Class of Biologic Drugs Based on Proprietary T cell receptor (TCR) Technology
10:30 (30 mins)
David Krige, ImmunoCore  
Phenotypic high-content screen measuring aggregate clearance in neurodegenerative diseases. Speaker - Emilie Bureau, MRCT
10:30
10:35 10:35
10:40 10:40
10:45 10:45
10:50 10:50
10:55 10:55
11:00 Coffee Break in The Exhibition Hall Coffee Break in The Exhibition Hall Coffee Break in The Exhibition Hall 11:00
11:05 11:05
11:10 11:10
11:15 11:15
11:20 11:20
11:25 11:25
11:30 Chemical Tools to Manipulate Bacterial Virulence
11:30 (30 mins)
Stephan Seiber, TU Munich  
Confocal High Content Screening of Cardiac and Liver Microtissues for the Improved Prediction of Drug Induced Toxicity
11:30 (30 mins)
Paul Walker, Cyprotex  
TBC
11:30 (30 mins)
Martin Pule, UCL  
High-content screening:How to easily select meaningful feature combinations. Speaker - Lope Florez, Genedata
Labcyte Workshop - Introduction to TRACK 2
11:30
11:35 11:35
11:40 From Routine to Extreme Cherry Picking. Design of New Acoustically Compatible Storage Tubes for Liquid Samples. Speaker - Clive Green, AstraZeneca
11:40
11:45 11:45
11:50 11:50
11:55 11:55
12:00 Poster Tasters
Chloe Koulouris - University of Sussex - Characterisation of serine racemase as a novel approach to modulating NMDA receptor function Gina Washbourn - University of Liverpool - The Synthesis and Biological Evaluation of Carbamoyl Triazoles as Potential Antituberculosis Protease Inhibitors
Poster Tasters
Eve Rogers - University of Liverpool - Exploring the Potential of the Physico-Mechanical Environment and Circadian Timing in Adult Stem Cell Differentiation. Matthew Burnham - AstraZeneca - Characterisation of stem cell derived cardiomyocyte spheroids using the CardioExcyte platform.
Poster Tasters
Arune Balaikaite - MRC Technology - T-cell epitopes, virus-like particles and extracellular loop fusions for challenging antibody generation. Aisha Alsfouk - Strathclyde University - Development of selective IKK╬▒ inhibitors as a treatment for prostate cancer therapy
Drug combinations as potential oncology therapeutics:Data analysis with Genedata Screener. Speaker - Michelle Newman, MRCT
12:00
12:05 12:05
12:10 12:10
12:15 Echo-MS A Versatile Platform for Ultrafast Mass Spectrometry Analysis in Drug Discovery. Speaker - Ian Sinclair, AstraZeneca
12:15
12:20 12:20
12:25 12:25
12:30 Snapshots (max 5 companies)
Takara Bio Europe
Professor Geny Groothius presents: Precision-cut tissue slices as translational and predictive ex vivo model for ADME and toxicity. Sponsored by Takara Bio...[More]
2016-10-13 12:30:002016-10-13 13:00:00Europe/LondonTakara Bio EuropeSession at 10th Anniversary Drug Discovery 2016 https://www.myeventflo.com/eventflo.asp?evID=1918OnlineSanj Kumar, ELRIGinfo@elrig.org
Snapshots (max 5 companies)
Simplifying synergy: Combination screens. Speaker - John Vincent, AstraZeneca
12:30
12:35 12:35
12:40 12:40
12:45 12:45
12:50 12:50
12:55 12:55
13:00 Lunch in The Exhibition Hall (Exhibition, Posters, Lunchtime Workshops?) 13:00
13:05 13:05
13:10 13:10
13:15 13:15
13:20 13:20
13:25 13:25
13:30 13:30
13:35 13:35
13:40 13:40
13:45 13:45
13:50 13:50
13:55 13:55
14:00 14:00
14:05 14:05
14:10 14:10
14:15 14:15
14:20 14:20
14:25 14:25
14:30 Drug Safety in Drug Development
14:30 (45 mins)
Keynote Speaker: Munir Pirmohamed , Drug Safety in Drug Development - THURS  
Please go to Keynote Room 3 Munir Pirmohamed , Drug Safety in Drug Development
Please go to Keynote Room 3 Munir Pirmohamed , Drug Safety in Drug Development
14:30
14:35 14:35
14:40 14:40
14:45 14:45
14:50 14:50
14:55 14:55
15:00 15:00
15:05 15:05
15:10 15:10
15:15 Beyond Small Molecule Inhibition: New Possibilities Through Induced Intracellular Protein Degradation
15:15 (30 mins)
John Harling, GSK  
Application of an In vitro Human Airway Epithelial 3D Model for the Detection of Lung Irritancy Following Drug Treatment
15:15 (30 mins)
Ellinor Hornberg, AstraZeneca  
Circulating tumour cells as a versatile liquid biopsy to manage cancer patient treatment and explore the biology of metastases
15:15 (30 mins)
Caroline Dive, Manchester University  
15:15
15:20 15:20
15:25 15:25
15:30 15:30
15:35 15:35
15:40 15:40
15:45 Small-Molecule Stabilization of 14-3-3 PPls: Possible New Approaches in Cancer, Cystic Fibrosis and Parkinson's Disease.
15:45 (30 mins)
Christian Ottman, Eindhoven  
High-Efficiency Cellular Reprogramming with Microfluidics for Patient-Specific Disease Modelling
15:45 (30 mins)
Nicola Elvassore, UCL  
Analysis of Reciprocal Tumour-Stroma Signalling by Cell-Specific Phosphoproteomics
15:45 (30 mins)
Claus Jorgensen, Cancer Research UK Manchester Institute  
15:45
15:50 15:50
15:55 15:55
16:00 16:00
16:05 16:05
16:10 16:10
16:15 From Fragment Hits to Selective Nanomolar Inhibitors of Human PAICS Without X-ray
16:15 (30 mins)
Andy Merritt, MRC Technology  
Intestinal organoids: disease modelling and regenerative medicine
16:15 (30 mins)
Vivian Li, The Francis Crick Institute  
Immunotherapy in the 21st Century: A Game Changing Paradigm in Oncology
16:15 (30 mins)
Thierry Wurch, Servier  
16:15
16:20 16:20
16:25 16:25
16:30 16:30
16:35 16:35
16:40 16:40
16:45 16:45-17:45 Poster Session 17.00 - 17.30 Dragons Den 17:00-19:00 Networking/Drinks Reception 16:45
16:50 16:50
16:55 16:55
17:00 17:00
17:05 17:05
17:10 17:10
17:15 17:15
17:20 17:20
17:25 17:25
17:30 17:30
17:35 17:35
17:40 17:40
17:45 17:45
17:50 17:50
17:55 17:55
18:00 18:00
18:05 18:05
18:10 18:10
18:15 18:15
18:20 18:20
18:25 18:25
18:30 GALA CELEBRATION at The Museum of Liverpool 18.30 - Welcome Drinks & Canapes 21.00 - Close 18:30
18:35 18:35
18:40 18:40
18:45 18:45
18:50 18:50
18:55 18:55
19:00 19:00
19:05 19:05
19:10 19:10
19:15 19:15
19:20 19:20
19:25 19:25
19:30 19:30
19:35 19:35
19:40 19:40
19:45 19:45
19:50 19:50
19:55 19:55
20:00 20:00
20:05 20:05
20:10 20:10
20:15 20:15
20:20 20:20
20:25 20:25
20:30 20:30
20:35 20:35
20:40 20:40
20:45 20:45
20:50 20:50
20:55 20:55
21:00 21:00