Tuesday 2 April
3 April
Presentation Keynote Chair Plenary Keynote Forum /
Workshop
Exhibitor
[Schedule with Tracks only]
DAY 1The AuditoriumThe Boulind SuiteMAB G12
DAY 2
DAY 1The AuditoriumThe Boulind SuiteMAB G12
DAY 2
08:00 Arrival, registration & welcome coffee 08:00
08:05 08:05
08:10 08:10
08:15 08:15
08:20 08:20
08:25 08:25
08:30 08:30
08:35 08:35
08:40 08:40
08:45 08:45
08:50 08:50
08:55 08:55
09:00 Conference welcome
Conference Welcome
09:00 (10 mins)
Jonathan Hutchinson, GlaxoSmithKline  Darren Cawkill, Apollo Therapeutics 
09:00
09:05 09:05
09:10 Keynote Speaker
Blue skies research to commercial outputs and patient benefits
09:10 (45 mins)
Prof Steve Jackson, University of Cambridge 
09:10
09:15 09:15
09:20 09:20
09:25 09:25
09:30 09:30
09:35 09:35
09:40 09:40
09:45 09:45
09:50 09:50
09:55 Coffee Break 09:55
10:00 10:00
10:05 10:05
10:10 10:10
10:15 10:15
10:20 10:20
10:25 10:25
10:30 Session Chair Introductions - New technologies and innovations in drug discovery
Session Introduction
10:30 (15 mins)
Andrew Leach, European Bioinformatics Institute  Pamela Williams, Astex Pharmaceuticals 
Session Chair Introductions - Where are new drug target hypotheses coming from?
Session Introduction
10:30 (5 mins)
Euan Stronach, GlaxoSmithKline  Nadine Clemo, Apollo Therapeutics 
Careers in Drug Discovery: Networking with purposeAre you a post doc, PhD student or early career professional (ECP) scientist looking to start or build your career in drug discovery? If so, understanding how to network with purpose and effectively build your professional network may help benefit your current role, provide the opening for your next collaboration, funding opportunity or step in your career We invite you join us at our ECP workshop event at ELRIG Research & Innovation 2019 • Discover how networking is an important and valuable skill for researchers • Learn how to prepare for effective networking at conferences and meetings • Hear the Dos and Don’ts of successful networking • Practice and refine your networking skills with other ECP scientists & expand your network 10:30
10:35 Where are new drug target hypotheses coming from?
Analysing human genetic influences on tens of thousands of human traits to find new drug targets
10:35 (40 mins)
Jeff Barrett, Genomics plc 
10:35
10:40 10:40
10:45 New Technologies & Innovations in Drug Discovery and Development
The role of computer simulations in drug design
10:45 (30 mins)
Prof Jon Essex, University of Southampton 
10:45
10:50 10:50
10:55 10:55
11:00 11:00
11:05 11:05
11:10 11:10
11:15 New Technologies & Innovations in Drug Discovery and Development
Leveraging Functional Genomics for Target Discovery
11:15 (30 mins)
Samantha Peel, AstraZeneca 
Where are new drug target hypotheses coming from?
Clinic to Drug Discovery and back: Reverse Translation in Cancer Therapy
11:15 (30 mins)
Prof Bissan Al-Lazikani, ICR 
11:15
11:20 11:20
11:25 11:25
11:30 11:30
11:35 11:35
11:40 11:40
11:45 Promega UK Ltd
New assay tools for protein degradation - 5 key steps for monitoring PROTAC activity PRESENTER - Dr Craig Malcolm ABSTRACT - Standard approaches to PROTAC characterisation using endpoint assays to mon...[More]
Pelago Bioscience AB
CETSA guided medicinal chemistry and lead generation PRESENTER - Stina Lundgren
11:45
11:50 LabLogic Systems Limited
Presenter - Lucy Farmer
Technology Spotlight Presentations 11:50
11:55 Svar Life Science
Biologically relevant cell-based assays: The iLite difference PRESENTER - Libby Naylor, Regional Sales Manager, Svar Life Science AB ABSTRACT - Cell-based assays for screening, potency and immunogenic...[More]
11:55
12:00 Lunch & Poster Walk 12:00
12:05 12:05
12:10 12:10
12:15 12:15
12:20 12:20
12:25 12:25
12:30 12:30
12:35 12:35
12:40 12:40
12:45 12:45
12:50 12:50
12:55 12:55
13:00 13:00
13:05 13:05
13:10 13:10
13:15 13:15
13:20 13:20
13:25 13:25
13:30 New Technologies & Innovations in Drug Discovery and Development
From target identification to clinical trials: a journey of proteomics in drug discovery
13:30 (30 mins)
Gitte Neubauer , Cellzome, a GSK company 
Where are new drug target hypotheses coming from?
Prioritisation of oncology therapeutic targets using CRISPR-Cas9 screening
13:30 (30 mins)
Dr Mathew Garnett, Wellcome Sanger Institute 
13:30
13:35 13:35
13:40 13:40
13:45 13:45
13:50 13:50
13:55 13:55
14:00 Poster Spotlight Presentations
G6b-B a new receptor for platelet production and function. Untangling post-translational modifications using mass spectrometry enables crystal structure determination in complex with ligand
14:00 (15 mins)
Dr Mark Abbott, Peak Proteins Ltd 

Solving target protein production challenges
14:15 (15 mins)
Dr Stefanie Reich, Domainex Ltd 
Poster Spotlight Presentations
CRUK-MedImmune Alliance Laboratory (CMAL) : A Unique Partnership in the Discovery and Development of Novel Biologics
14:00 (15 mins)
Miss Michelle Barnard, CRUK-MedImmune Alliance Laboratory 

High-content imaging of myelin phagocytosis by human monocyte-derived microglia to investigate pathways relevant for neurotrauma, neuroinflammation, neuropsychiatry and neurodegeneration
14:15 (15 mins)
Professor Nicholas Barnes, Celentyx 
14:00
14:05 14:05
14:10 14:10
14:15 14:15
14:20 14:20
14:25 14:25
14:30 New Technologies & Innovations in Drug Discovery and Development
Artificial Intelligence in Drug Design
14:30 (30 mins)
Ola Engkvist, AstraZeneca 
Where are new drug target hypotheses coming from?
Artificial Intelligence for identifying novel therapeutic targets, biomarkers and drug repositioning opportunities
14:30 (30 mins)
Dr Namshik Han, Milner Therapeutics Institute, University of Cambridge 
14:30
14:35 14:35
14:40 14:40
14:45 14:45
14:50 14:50
14:55 14:55
15:00 Cisbio
HTRF Assays + Reagents for Immuno-Oncology Drug Discovery PRESENTER - Louise Affleck PhD, UK Team Leader ABSTRACT - Presentation Summary The HTRF assay platform is robust and flexible and can be appli...[More]
Technology Spotlight Presentations 15:00
15:05 Nexcelom Bioscience Ltd
PRESENTER - Sun Yung PhD
15:05
15:10 Miltenyi Biotec Ltd
PRESENTER - Dr Matthew MacKenzie, Flow Cytometry Application Specialist.
15:10
15:15 Coffee 15:15
15:20 15:20
15:25 15:25
15:30 15:30
15:35 15:35
15:40 15:40
15:45 New Technologies & Innovations in Drug Discovery and Development
SiLC-MS (Single Live Cell Mass Spectrometry) analysis in the context of drug discovery
15:45 (30 mins)
Carla Newman, GlaxoSmithKline 

Expanding the scope of structure-based drug design with cryoEM
16:15 (30 mins)
Stacey Southall, Sosei Heptares 

Activity-Directed Synthesis: a platform for the discovery of bioactive small molecules
16:45 (30 mins)
Dr George Karageorgis, University of Leeds 
Where are new drug target hypotheses coming from?
Drugging transcription: Progress and potential for treating human immune dysfunction
15:45 (30 mins)
Rabinder Prinjha, GSK 

Target Validation and Drug Discovery for KMO inhibitors.
16:15 (30 mins)
Iain Uings , GlaxoSmithKline  Damian Mole, University of Edinburgh 

New drug targets: the academic accidents!
16:45 (30 mins)
Clare Bryant, University of Cambridge 
15:45
15:50 15:50
15:55 15:55
16:00 16:00
16:05 16:05
16:10 16:10
16:15 16:15
16:20 16:20
16:25 16:25
16:30 16:30
16:35 16:35
16:40 16:40
16:45 16:45
16:50 16:50
16:55 16:55
17:00 17:00
17:05 17:05
17:10 17:10
17:15 Networking & Drinks Event 17:15
17:20 17:20
17:25 17:25
17:30 17:30
17:35 17:35
17:40 17:40
17:45 17:45
17:50 17:50
17:55 17:55
18:00 18:00
18:05 18:05
18:10 18:10
18:15 18:15
18:20 18:20
18:25 18:25
18:30 18:30
18:35 18:35
18:40 18:40
18:45 18:45
18:50 18:50
18:55 18:55
19:00 19:00