2 September
Thursday 3 September
Presentation Keynote Chair Plenary Keynote Forum /
Workshop
Exhibitor
DAY 1
Exhibition AreaPattingham
Oncology Drug Targets
Beckbury
Cell and Gene Therapy
Wenlock
New Biological Drugs & Technologies
Ironbridge
Phenotypic Discovery & Cell Imaging
Coalport
Technology Forums
DAY 2
DAY 1
Exhibition AreaPattingham
Oncology Drug Targets
Beckbury
Cell and Gene Therapy
Wenlock
New Biological Drugs & Technologies
Ironbridge
Phenotypic Discovery & Cell Imaging
Coalport
Technology Forums
DAY 2
08:00 Arrival, Registration & Coffee 08:00
08:05 08:05
08:10 08:10
08:15 08:15
08:20 08:20
08:25 08:25
08:30 08:30
08:35 08:35
08:40 08:40
08:45 08:45
08:50 08:50
08:55 08:55
09:00 09:00
09:05 09:05
09:10 Session Chair Introduction
Chairs: Herbie Newell, Newcastle University  Hamish Ryder, Cancer Research Technology 
Session Chair Introduction
Chairs: Aniz Girach, NightstaRx  Angela Gritti, San Raffaele Telethon Institute for Gene Therapy (TIGET) 
Session Chair Introduction
Chairs: Katy Kettleborough, MRC Technology Dr Lutz Jermutus, MedImmune 
Session Chair Introduction
Chairs: Steve Ludbrook, GlaxoSmithKline Dr Marc Bickle, Max Planck Institute of Molecular Cell Biology and Genetics 
Anti-Infectives
Chairs: Eddy Littler, Domainex Dr Ken Powell, Reviral 
09:10
09:15 “We Must Work Together To Catalyse the Generation of More Novel and More Affordable Cancer Treatments”
09:15 (45 mins)
Keynote Speaker: Prof Chas Bountra, SGC, University of Oxford 
How Stem Cells Signal to Host Immune Cells
09:15 (45 mins)
Keynote Speaker: Stefano Pluchino , Wellcome Trust-MRC Stem Cell Institute, University of Cambridge (UK) 
Towards a New Class of Biotherapeutics Based on Synthetic Genetic Polymers
09:15 (45 mins)
Keynote Speaker: Philipp Holliger , MRC Laboratory of Molecular Biology 
Phenotypic Screening to Identify Novel Targets for Discovery
09:15 (45 mins)
Keynote Speaker: Stephen Rees, AstraZeneca 
09:15
09:20 09:20
09:25 09:25
09:30 09:30
09:35 09:35
09:40 09:40
09:45 09:45
09:50 09:50
09:55 09:55
10:00 Optimising Oncology Drug Discovery via Partnerships Between Academia and Industry
10:00 (30 mins)
Neil Thompson, Astex Pharmaceuticals 
Hematopoietic Stem Cell Based Gene Therapy for the Treatment of Lysosomal Storage Disorders
10:00 (30 mins)
Alessandra Biffi, TIGET, IRCCS San Raffaele Scientific Institute 
Development of Cytotoxic Bicyclic Peptide Drug Conjugates and Applications in Molecular Targeted Cancer Therapy
10:00 (30 mins)
Dan Teufel, Bicycle Therapeutics 
Increasing Physiological Relevance, Increasing Information: High-Content Phenotypic Screening
10:00 (30 mins)
Dr Anne Carpenter, Broad Institute of Harvard and MIT 
10:00
10:05 10:05
10:10 10:10
10:15 10:15
10:20 10:20
10:25 10:25
10:30 Coffee Break 10:30
10:35 10:35
10:40 10:40
10:45 10:45
10:50 10:50
10:55 10:55
11:00 Building On an Atypical (PKC) Relationship – Innovative Drug Discovery Alliances in Oncology
11:00 (30 mins)
Christian Dillon, Cancer Research Technology Discovery Laboratory 
Accelerating Human iPSC in vitro Disease Modeling by Introducing Targeted Gene Mutations in Isogenic Cell Lines Through the CRISPR/Cas9 Nuclease System
11:00 (30 mins)
Vania Broccoli, Italian Research Council (CNR) and Ospedale San Raffaele 
How Information From the Study of Antibody Function Can be Used in the Discovery of Novel Small Molecule Therapeutics
11:00 (30 mins)
Tom Crabbe, UCB 
Compound Screening and Profiling in Cultured Human Tissues
11:00 (30 mins)
Leo Price, OcellO  
Future of HTS
Chairs: Uli Schopfer, Novartis 
11:00
11:05 11:05
11:10 11:10
11:15 11:15
11:20 11:20
11:25 11:25
11:30 Poster Tasters
Poster Tasters
Poster Tasters
Poster Tasters
11:30
11:35 11:35
11:40 11:40
11:45 11:45
11:50 11:50
11:55 11:55
12:00 Snapshot Presentations
Session: Oncology Drug Targets
Snapshot Presentations
Session: Cell and Gene Therapy
Snapshot Presentations
Session: New Biological Drugs & Technologies
Snapshot Presentations
Session: Phenotypic Discovery & Cell Imaging
12:00
12:05 12:05
12:10 12:10
12:15 12:15
12:20 12:20
12:25 12:25
12:30 Lunch - Exhibition - Posters - Workshops Enzymology Used Throughout Drug Discovery
Chairs: Geoff Holdgate, AstraZeneca 
12:30
12:35 12:35
12:40 12:40
12:45 12:45
12:50 12:50
12:55 12:55
13:00 13:00
13:05 13:05
13:10 13:10
13:15 13:15
13:20 13:20
13:25 13:25
13:30 13:30
13:35 13:35
13:40 13:40
13:45 13:45
13:50 13:50
13:55 13:55
14:00 The Development of New Therapeutics for respiratory inflammation
14:00 (60 mins)
Prof Tracy Hussell, Manchester Collaborative Centre for Inflammation Research 
14:00
14:05 14:05
14:10 14:10
14:15 14:15
14:20 14:20
14:25 14:25
14:30 14:30
14:35 14:35
14:40 14:40
14:45 14:45
14:50 14:50
14:55 14:55
15:00 Targeting Oxygenases for the Regulation of Protein Biosynthesis
15:00 (30 mins)
Christopher Schofield, Oxford University 
Modelling Cardiovascular Disease with Pluripotent Stem Cells: a High-Content Approach
15:00 (30 mins)
Gabor Foldes, National Heart and Lung Institute, Imperial College London 
XTEN Protein Polymer for Half-Life Extension and Tumor Drug Delivery
15:00 (30 mins)
Volker Schellenberger, Amunix 
Mass Spectrometry Imaging in Drug Discovery – Bridging Between Cells and Tissues
15:00 (30 mins)
Peter Webborn, AstraZeneca R&D  
Protein-Protein Interaction in Drug Discovery
Chairs: Dr Christian Ottman, Technical University Eindhoven 
15:00
15:05 15:05
15:10 15:10
15:15 15:15
15:20 15:20
15:25 15:25
15:30 Chemical Probes for the Bromodomain of the BRPF Family
15:30 (30 mins)
Paul Fish, UCL School of Pharmacy  
Adoptive T Cell Therapy for Cancer
15:30 (30 mins)
Dr David Gilham, Manchester University 
Fine-Tuned T Cell Receptors for Cancer Immunotherapy
15:30 (30 mins)
Bent Jakobsen, Adaptimmune 
Phenotypic Discovery Using Machine Learning and Image Analysis Methods
15:30 (30 mins)
Peter Horvath, Biological Research Centre of the Hungarian Academy of Sciences 
15:30
15:35 15:35
15:40 15:40
15:45 15:45
15:50 15:50
15:55 15:55
16:00 Fragment-Based Lead Generation of Reversible Inhibitors for Lysine-Specific Demethylases
16:00 (30 mins)
Ulf Bremberg, Beactica 
Gene Therapy for Choroideremia, an Inherited Cause of Blindness
16:00 (30 mins)
Alun Barnard, Oxford University 
PBD-Based Antibody Drug Conjugates
16:00 (30 mins)
John Hartley, University College London 
KNIME Image Processing - Integrative Open-Source BioImage Analysis
16:00 (30 mins)
Christian Dietz, University of Konstanz 
16:00
16:05 16:05
16:10 16:10
16:15 16:15
16:20 16:20
16:25 16:25
16:30 Close of Conference
Prize Giving Prize Draw
16:30
16:35 16:35
16:40 16:40
16:45 16:45
16:50 16:50
16:55 16:55
17:00 17:00
17:05 17:05
17:10 17:10
17:15 17:15
17:20 17:20
17:25 17:25
17:30 17:30
17:35 17:35
17:40 17:40
17:45 17:45
17:50 17:50
17:55 17:55
18:00 18:00
18:05 18:05
18:10 18:10
18:15 18:15
18:20 18:20
18:25 18:25
18:30 18:30
18:35 18:35
18:40 18:40
18:45 18:45
18:50 18:50
18:55 18:55
19:00 19:00