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Prof Sarah Tabrizi

Prof Sarah Tabrizi
Prof Sarah Tabrizi

Profile of Prof Sarah Tabrizi

Sarah Tabrizi is Professor of Clinical Neurology and joint Head of Department of Neurodegenerative disease at the UCL Institute of Neurology, Honorary Consultant Neurologist at the National Hospital of Neurology and Neurosurgery, Queen Square, London, and Director of the UCL Huntington’s Disease Centre. In addition to basic bench science which focuses on basic cellular mechanisms of neurodegeneration focusing on Huntington’s disease (HD), she also leads a large translational research programme in HD that is working towards finding effective disease-modifying treatments. She was the PI of TRACK-HD and Track-On HD, both major international research initiatives aimed at understanding the neurobiology of the neurodegenerative changes in premanifest and early stage HD gene carriers. She was global clinical PI on the world’s first gene silencing study for HD using anti-sense oligonucleotide therapy, sponsored by Ionis pharmaceuticals, the safety study for which successfully completed in December 2017. Sarah has published over 290 peer-reviewed publications to date, has an H-index of 70, and her research work has been the subject of articles in NEJM, The Economist, Scientific American, and The Lancet. In 2014, she was elected a Fellow of the UK Academy of Medical Sciences. In 2017 she received the seventh Leslie Gehry Brenner Prize for Innovation in Science awarded by the Hereditary Disease Foundation, and was appointed as a Principal Investigator at the UK Dementia Research Institute Hub. In 2018 she received the Cotzias Award from the Spanish Society of Neurology.


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