Drug Discovery Digital 2020 - Connect - Learn - Discover

Dr James O'Connell

Dr James O'Connell
Dr James O'Connell

Presentations at Drug Discovery Digital 2020 - Connect - Learn - Discover

Profile of Dr James O'Connell

Dr. James O'Connell is currently Director of Target Based Drug Screening at UCB’s UK site in Slough. This comprises of two groups, Molecular Pharmacology and SPR and biophysical methods that test both small molecules and biologics. After joining Celltech (now UCB) from GD Searle in 1986 he helped to establish small molecule screening using fluorescent substrates for their MMP project before leading the enzymology screening group. Following his work on kinases he chaired the first IIR kinase workshop on screening methodologies.
Latterly, his work has focused on protein: protein interactions and in particular on their inhibition by fragments. He successfully led a team in the discovery and development of the first orally available small molecule inhibitor of TNF. He continued to work on protein :protein interactions, before taking up his current role. Additionally, he has been a member of the Scientific Advisory Board for Cyclofluidic and lectured on enzyme kinetics at Brunel university.


Dr Andrew Sullivan
Assay Development Scientist
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