Drug Discovery Digital 2020 - Connect - Learn - Discover

Dr Katie Burnham

Dr Katie Burnham
Dr Katie Burnham
Postdoctoral Fellow
Sanger Institute
Speaker

Presentations at Drug Discovery Digital 2020 - Connect - Learn - Discover

Wed14  Oct11:35am(30 mins)
A multi-omic approach to investigate variation in the host sepsis response

Session: Multi Omic approaches to deliver new medicines
Room: Conference Hall

Profile of Dr Katie Burnham

Katie is a Postdoctoral Fellow in Dr Emma Davenport’s team in the Human Genetics programme at the Wellcome Sanger Institute. She obtained her PhD in Clinical Medicine at the Wellcome Centre for Human Genetics in Oxford, in Professor Julian Knight’s lab, where she subsequently conducted her first post-doc.
The Davenport group focuses on integrating functional genomics and clinical data to understand the contribution of genetics to patient heterogeneity and response to treatment. Katie is particularly interested in the regulation of gene expression in the context of the immune response, and its modulation by environmental perturbations. Her research focuses on applying functional genomics methods to explore the host sepsis response as part of the Genomic Advances in Sepsis (GAinS) study. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, and is a major cause of death both in the UK and worldwide. She uses multi-omics data sets (genotyping, transcriptomics, proteomics) on large patient cohorts to explore disease subgroups revealed by host transcriptomics and associated with clinical outcomes that could present an opportunity for a precision medicine approach to sepsis management.
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