Programme : Presentations by Speaker

Alun Barnard

Gene Therapy for Choroideremia, an Inherited Cause of Blindness
Thu3  Sep04:00pm(30 mins)
Alun Barnard Alun Barnard  
Room: Beckbury

Neil Benson

The Role of Systems Biology / Pharmacology in Choosing and Validating Targets
Wed2  Sep10:00am(30 mins)
Neil Benson Neil Benson  
Room: Wenlock

Alessandra Biffi

Hematopoietic Stem Cell Based Gene Therapy for the Treatment of Lysosomal Storage Disorders
Thu3  Sep10:00am(30 mins)
Alessandra Biffi Alessandra Biffi  
Room: Beckbury

Prof Chas Bountra

Keynote: “We Must Work Together To Catalyse the Generation of More Novel and More Affordable Cancer Treatments”
Thu3  Sep09:15am(45 mins)
Prof Chas Bountra Prof Chas Bountra  
Room: Pattingham

Ulf Bremberg

Fragment-Based Lead Generation of Reversible Inhibitors for Lysine-Specific Demethylases
Thu3  Sep04:00pm(30 mins)
Ulf Bremberg Ulf Bremberg  
Room: Pattingham

Vania Broccoli

Accelerating Human iPSC in vitro Disease Modeling by Introducing Targeted Gene Mutations in Isogenic Cell Lines Through the CRISPR/Cas9 Nuclease System
Thu3  Sep11:00am(30 mins)
Vania  Broccoli Vania Broccoli  
Room: Beckbury

Dr Anne Carpenter

Increasing Physiological Relevance, Increasing Information: High-Content Phenotypic Screening
Thu3  Sep10:00am(30 mins)
Dr Anne  Carpenter Dr Anne Carpenter  
Room: Ironbridge

Katie Chapman

Novel Inhibitors of MAP4K4 (HGK), an Acute Therapy to Prevent Cardiac Muscle Cell Death Following Myocardial Infarction
Wed2  Sep11:00am(30 mins)
Katie Chapman Katie Chapman  
Room: Pattingham

Steven Charlton

The Kinetics of Drug-Receptor Binding: Why It Is Important and How We Can Measure It
Wed2  Sep10:00am(30 mins)
Steven Charlton Steven Charlton  
Room: Ironbridge

Ken Chien

Synthetic Chemically modified mRNA (modRNA): Towards A New Technology Platform for Cardiovascular Biology and Medicine
Wed2  Sep03:30pm(30 mins)
Ken Chien Ken Chien  
Room: Pattingham

Miguel Conde

Nanobodies in Cell-Based Screening
Wed2  Sep04:00pm(30 mins)
Miguel Conde Miguel Conde  
Room: Ironbridge

Tom Crabbe

How Information From the Study of Antibody Function Can be Used in the Discovery of Novel Small Molecule Therapeutics
Thu3  Sep11:00am(30 mins)
Tom Crabbe Tom Crabbe  
Room: Wenlock

Christian Dietz

KNIME Image Processing - Integrative Open-Source BioImage Analysis
Thu3  Sep04:00pm(30 mins)
Christian Dietz Christian Dietz  
Room: Ironbridge

Christian Dillon

Building On an Atypical (PKC) Relationship – Innovative Drug Discovery Alliances in Oncology
Thu3  Sep11:00am(30 mins)
Christian  Dillon Christian Dillon  
Room: Pattingham

Pete DiMaggio

Mass Spectrometry-Based Discovery Tools for Epigenetics
Wed2  Sep11:00am(30 mins)
Pete DiMaggio Pete DiMaggio  
Room: Wenlock

Michael Edwards

New Targets for Virus-Induced Asthma Exacerbations: From Bedside to Bench
Wed2  Sep04:00pm(30 mins)
Michael Edwards Michael Edwards  
Room: Wenlock

Paul Fish

Chemical Probes for the Bromodomain of the BRPF Family
Thu3  Sep03:30pm(30 mins)
Paul Fish Paul Fish  
Room: Pattingham

Gabor Foldes

Modelling Cardiovascular Disease with Pluripotent Stem Cells: a High-Content Approach
Thu3  Sep03:00pm(30 mins)
Gabor  Foldes Gabor Foldes  
Room: Beckbury

Dr David Gilham

Adoptive T Cell Therapy for Cancer
Thu3  Sep03:30pm(30 mins)
Dr David  Gilham Dr David Gilham  
Room: Beckbury

Dr Frederick Goldberg

Design of Novel Building Blocks to Enhance Drug Discovery
Wed2  Sep10:00am(30 mins)
Dr Frederick Goldberg Dr Frederick Goldberg  
Room: Beckbury

John Hartley

PBD-Based Antibody Drug Conjugates
Thu3  Sep04:00pm(30 mins)
John Hartley John Hartley  
Room: Wenlock

Christian Heinis

Phage Selection of Bicyclic Peptides for Therapeutic Application
Wed2  Sep04:00pm(30 mins)
Christian  Heinis Christian Heinis  
Room: Beckbury

Julie Holder

Efficacy and Toxicity Assays Using iPS cells - Utilising Cells Reset to the Manufacturers Default Setting
Wed2  Sep03:00pm(30 mins)
Julie Holder Julie Holder  
Room: Ironbridge

Philipp Holliger

Keynote: Towards a New Class of Biotherapeutics Based on Synthetic Genetic Polymers
Thu3  Sep09:15am(45 mins)
Philipp  Holliger Philipp Holliger  
Room: Wenlock

Peter Horvath

Phenotypic Discovery Using Machine Learning and Image Analysis Methods
Thu3  Sep03:30pm(30 mins)
Peter Horvath Peter Horvath  
Room: Ironbridge

Tobias Huber

Unravelling the Molecular Mechanisms of Proteinuria
Wed2  Sep03:00pm(30 mins)
Tobias Huber Tobias Huber  
Room: Pattingham

Norbert Hübner

The Role of Post-Transcriptional Regulation in Cardiac Disease
Wed2  Sep04:00pm(30 mins)
Norbert  Hübner Norbert Hübner  
Room: Pattingham

Prof Tracy Hussell

The Development of New Therapeutics for respiratory inflammation
Thu3  Sep02:00pm(60 mins)
Prof Tracy Hussell Prof Tracy Hussell  
Session : Plenary Keynote
Room: Ironbridge

Bent Jakobsen

Fine-Tuned T Cell Receptors for Cancer Immunotherapy
Thu3  Sep03:30pm(30 mins)
Bent Jakobsen Bent Jakobsen  
Room: Wenlock

Mattias Karlsson

Functional Screening of Network Activity in Primary Neuronal Cultures Using a Novel Phenotypic Assay Platform
Wed2  Sep03:30pm(30 mins)
Mattias Karlsson  
Room: Ironbridge

Daniel P. Kelly

Keynote: Myocyte Lipotoxicity: A Chemical Biology Approach
Wed2  Sep09:15am(45 mins)
Daniel P.  Kelly Daniel P. Kelly  
Room: Beckbury

Kim Kelly

Nanotechnology, Imaging and Targeted Drug Therapy in Cardiac Pathology
Wed2  Sep10:00am(30 mins)
Kim  Kelly Kim Kelly  
Room: Pattingham

Chris Lord

The Application of Synthetic Lethality to Cancer Treatment
Wed2  Sep03:30pm(30 mins)
Chris Lord Chris Lord  
Room: Wenlock

Julio Martin Plaza

SLAS Author Workshop: How to Get Your Work Published
Wed2  Sep01:00pm(60 mins)
Julio Martin Plaza  
Room: Jackfield

Jon Moore

The Impact of CRISPR/Cas9 on Target Identification and Validation
Wed2  Sep03:00pm(30 mins)
Jon Moore Jon Moore  
Room: Wenlock

James Murray

All in Good Time, Exploiting Residence Time to Improve Fragment Based Drug Discovery
Wed2  Sep03:30pm(30 mins)
James  Murray James Murray  
Room: Beckbury

Stefano Pluchino

Keynote: How Stem Cells Signal to Host Immune Cells
Thu3  Sep09:15am(45 mins)
Stefano  Pluchino Stefano Pluchino  
Room: Beckbury

Leo Price

Compound Screening and Profiling in Cultured Human Tissues
Thu3  Sep11:00am(30 mins)
Leo  Price Leo Price  
Room: Ironbridge

Stephen Rees

Keynote: Phenotypic Screening to Identify Novel Targets for Discovery
Thu3  Sep09:15am(45 mins)
Stephen Rees Stephen Rees  
Room: Ironbridge

Friedrich Reinhard

Keynote: Target Identification and Target Engagement: Applications in Drug Discovery
Wed2  Sep09:15am(45 mins)
Friedrich  Reinhard Friedrich Reinhard  
Room: Wenlock

Volker Schellenberger

XTEN Protein Polymer for Half-Life Extension and Tumor Drug Delivery
Thu3  Sep03:00pm(30 mins)
Volker  Schellenberger Volker Schellenberger  
Room: Wenlock

Christopher Schofield

Targeting Oxygenases for the Regulation of Protein Biosynthesis
Thu3  Sep03:00pm(30 mins)
Christopher  Schofield Christopher Schofield  
Room: Pattingham

Dan Teufel

Development of Cytotoxic Bicyclic Peptide Drug Conjugates and Applications in Molecular Targeted Cancer Therapy
Thu3  Sep10:00am(30 mins)
Dan  Teufel Dan Teufel  
Room: Wenlock

David Thomas

Tackling Protein Trafficking Diseases
Wed2  Sep02:00pm(60 mins)
David  Thomas David Thomas  
Session : Plenary Keynote
Room: Ironbridge

Neil Thompson

Optimising Oncology Drug Discovery via Partnerships Between Academia and Industry
Thu3  Sep10:00am(30 mins)
Neil Thompson Neil Thompson  
Room: Pattingham

Chris Torrance

Keynote: Phenotypic Screening for Novel Druggable Targets Using "Protein-Interference"
Wed2  Sep09:15am(45 mins)
Chris Torrance Chris Torrance  
Room: Ironbridge

Dr Mike Waring

Structure-Kinetic Relationships: Investigating the Molecular Basis for Optimising Drug-Target Residence Time
Wed2  Sep03:00pm(30 mins)
Dr Mike  Waring Dr Mike Waring  
Room: Beckbury

Peter Webborn

Mass Spectrometry Imaging in Drug Discovery – Bridging Between Cells and Tissues
Thu3  Sep03:00pm(30 mins)
Peter Webborn Peter Webborn  
Room: Ironbridge

David Winpenny

Biased Ligand Quantification in Drug Discovery: From Theory to High Throughput Screening to Identify New Biased µ Opioid Receptor Agonists
Wed2  Sep11:00am(30 mins)
David Winpenny David Winpenny  
Room: Ironbridge

Paul Wyatt

Phenotypic Drug Discovery: With A Lot of Help From Our Friends!
Wed2  Sep11:00am(30 mins)
Paul  Wyatt Paul Wyatt  
Room: Beckbury

Damian Young

Keynote: Using Diversity-Oriented Synthesis to Enable Fragment-Based Lead Discovery
Wed2  Sep09:15am(45 mins)
Damian Young Damian Young  
Room: Pattingham
Programme

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