Poster
36

CyBio FeliX: Making Simple Western™ Technology … More Simple

Authors

R Mordue1; F Deakin2; C Hirst2; K Dodgson1; G Allenby1
1 Aurelia Bioscience Ltd, UK;  2 Analytik Jena AG, UK

Abstract

The
Simple-Western™ JESS is a capillary based automated western blot instrument
capable of running 24 samples from generation to results in approximately 5
hours. This throughput is advantageous compared to traditional western blot
systems that traditionally runs 10-20 samples, has 4-5 hours bench time, and
takes 24-48 hours to get results. Automation of the protein separation and
immunodetection process eliminates the error prone steps of traditional western
blotting and the associated software quickly processes the quantifiable data.
At Aurelia Bioscience, the Simple-Western™ JESS is a staple technique in a
repertoire of drug discovery methodologies. Therefore, our aim was to simplify
the Simple-Western™ procedure, increasing flexibility of a scientists workload
and reproducibility of JESS data, while also allowing inexperienced users to
access the technology. In order to examine the capabilities of the technology,
THAL-SNS-032 (a well studied PROTAC) was examined for its ability to degrade
CDK9 and compared with data previously generated for the Protein-Simple™
webinar “Advancing
Targeted Protein Degradation Research with Automated Western Blotting”.

Hosted By

ELRIG
The European Laboratory Research & Innovation Group Our Vision : To provide outstanding, leading edge knowledge to the life sciences community on an open access basis
Event Logo Find us on Facebook Follow us on Twitter

Get the App

Get this event information on your mobile by
going to the appstore or google play and search for 'elrig'
Login
Eventflo Home
copyright ELRIG, eventflo.co.uk, Labhoo Ltd 2003-2021