Poster
19

Introducing Multiplex and High Sensitivity Immunoassays for Characterization of SARS-CoV-2 Humoral Immunity

Authors

D Garcia-West1
1 ELRIG, UK

Abstract

Our scientists have developed several MILLIPLEX®
and Single Molecule Counting (SMC™) based SARS-CoV-2-specific immunoassay
kits in response to the COVID-19 research community’s growing needs for
research tools used to further our understanding of the novel coronavirus. These
qualitative Research Use Only (RUO) assays, which can detect antibodies against
SARS-CoV-2 antigens in human serum or plasma samples, are intended to empower
researchers performing vaccine efficacy, epidemiology, and population
studies.  Our new MILLIPLEX® SARS-CoV-2
panels can facilitate simultaneous detection of the SARS-CoV-2 Spike S1, Spike
S2, Receptor Binding Domain (RBD), and Nucleocapsid (N) proteins
and
antigen-specific IgM, IgG, or IgA antibody responses on the Luminex®
multiplex platform. They are well suited for examining the immune response to the virus over the
course of infection and recovery from COVID-19.  Meanwhile, our SMC™ SARS-CoV-2 kits offer the ability
to characterize viral antigen specific humoral immunity with greater
sensitivity
, such as in cases involving acute infections and subclinical immune
responses
.  For these new assays, data
are presented from human patient samples sets confirmed positive or negative
for COVID-19 by SARS-CoV-2 PCR tests. 
Overall, our new MILLIPLEX® and SMC™ assays can assist in
COVID-19 research efforts to help society overcome the current global pandemic.


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ELRIG
The European Laboratory Research & Innovation Group Our Vision : To provide outstanding, leading edge knowledge to the life sciences community on an open access basis
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