Schistosomiasis in Ogbese-Ekiti, re-infection after successful treatment with praziquantel


A Ogunlade2; C A Ologunde1
1 Department of Science Technology, The Federal Polytechnic, P.M.B. 5351, Ado – Ekiti, Nigeria;  2 The Federal Polytechnic Ado Ekiti, Nigeria


Urinary Schizostosomiasis infection is one of the major public health problem facing developing countries with school age children at great risk. Previous studies showed that Ogbese Ekiti is endemic for Urinary schistosomiasis. The impact of chemotherapy was evaluated using praziquantel (40mg/kg body weight) on S. haematobium among school pupils in Ogbese Ekiti, Ekiti state Nigeria. Urine samples were collected between the hours of 7.00am and 10.00 am. The number of eggs in 10ml of each urine sample was calculated from the means of two counts. At baseline one hundred and seventy two (172) pipils were screened for eggs of the S.haematobium out of which 75.6% were positive with high egg intensity ranging between 440-780 eggs/10ml of urine. Out of the one hundred and seventy two screened, thirty subjects with high egg intensity (440-780 eggs/10ml of urine) were treated with praziquantel in January 2009. After 10days post treatment, the urine sample of the thirty subjects were negative for S.haematobium. The subjects were monitored monthly for re-infection for seven consecutive months (February-August). Re-infection was first noticed in May. Keywords: Schistosomiasis, praziquantel, S.heamatobium, endemicity, Macrohaematuria Bulinus(B) globossus, cercariae

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