Poster
88

Doing More With Less: Breaking the Drug Discovery Bottleneck

Discussion

Nanotether Discovery Science (Nanotether) has developed a patented technology for rapidly developing multiplexed biological assays for use in high throughput screening and compound profiling.

Nanotether's technology utilises variable length DNA molecules as tethers for binding biomolecules in close proximity, thereby reducing the volume of proteins and ligands. Effectively, a nanoscale 'reaction chamber' is produced around each interaction pair, which enables very high density multiplex assays.

Protein targets are tethered to the end of one arm of a Y-shaped molecule, with the ligand attached to the second arm, hence increasing the effective concentration, whilst simultaneously reducing protein requirements. The ligand can be a small molecule, peptide or another protein, thereby enabling a broad range of targets, including protein-protein binding and epigenetics.

Hosted By

ELRIG
The European Laboratory Research & Innovation Group Our Vision : To provide outstanding, leading edge knowledge to the life sciences community on an open access basis
Event Logo Follow us on Twitter

Get the App

Get this event information on your mobile by
going to the appstore or google play and search for 'elrig'
Login
Eventflo Home
copyright ELRIG, eventflo.co.uk, Labhoo Ltd 2003-2021