DiscussionIn the search for valuable leads for newly identified targets in early drug discovery, well-designed high-throughput screening campaigns are among the critical first steps and can be decisive for the program success.
Accurate selection of the assay format reflecting the biological problem will increase the likelihood to identify target-specific hits.
Importantly, the source of the compound collection to be screened should be chosen carefully, to ensure the availability of high-quality and valuable hits.
Additionally, a through analysis of the high-throughput screening data can provide valuable information.
At Exquiron, advanced biology capabilities and automation are combined with a superior compound collection free of IP issues and dedicated data analysis tools, to provide an optimal start to a successful lead discovery.