Programme : Back to Mr Jean-Marc D'Angelo

BRET2 assay using the FDSS/μCELL: monitoring cell surface-receptor internalization and intracellular trafficking


After the publication of application note n°23 describing BRET1 technology and based on a study published in 2011, Pierre Fabre Research Institute recently implemented the more sensitive BRET2 technology to the FDSSµCell system for monitoring the internalization of the human dopaminergic D2s receptor, a prototypic G protein-coupled receptor (GPCR). The results of this work will be presented.
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