Programme : Back to Kate Enright
Poster
15

Understanding the effect of short term temperature excursions on cell therapies

Discussion

Cell Therapy Challenges

Industry shift towards advanced biologics and cell therapeutics

Large difference between three methods:
Traditional Process – Synthetic Chemistry / Small Molecule
Cell Based – Autologous Process
Cell Based- Allogeneic Process

Drugs are living cells and viability is key

Requires ultra cold chain (cryogenic) integrated throughout the process flow which differs from traditional

Scale-up issues from PI to PIII

Commercialization & regulation pathway which is largely undefined
Programme
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